Evidence map›Paper›PMID 33024470›Full record

ArticleJournal of arrhythmia2020

Twelve-lead and signal-averaged electrocardiographic parameters among beta-thalassemia major patients.

Dimitrios Patsourakos, Konstantinos A Gatzoulis, Constantina Aggeli, Sophia Delicou, Yannis Dimitroglou, Katerina Xydaki, Konstantinos Toutouzas, Aristeidis Androulakis, Dimitrios Tousoulis

Open access · goldAbstract read
In one paragraph

Article in Journal of arrhythmia, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
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  6. Review
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  8. Beta thalassemia major: the invaluable role of electrocardiography and echocardiography.The international journal of cardiovascular imaging · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Dimitrios PatsourakosState Department of Cardiology General Hospital of Athens Ippokrateio Athens Greece.ORCID https://orcid.org/0000-0003-3484-3041
Konstantinos A GatzoulisFirst Department of Cardiology General Hospital of Athens Ippokrateio, National and Kapodistrian University of Athens Athens Greece.ORCID https://orcid.org/0000-0002-6628-0303
Constantina AggeliFirst Department of Cardiology General Hospital of Athens Ippokrateio, National and Kapodistrian University of Athens Athens Greece.
Sophia DelicouThalassemia and Sickle Cell Unit General Hospital of Athens Ippokrateio Athens Greece.
Yannis DimitroglouFirst Department of Cardiology General Hospital of Athens Ippokrateio, National and Kapodistrian University of Athens Athens Greece.ORCID https://orcid.org/0000-0001-7340-5242
Katerina XydakiThalassemia and Sickle Cell Unit General Hospital of Athens Ippokrateio Athens Greece.
Konstantinos ToutouzasFirst Department of Cardiology General Hospital of Athens Ippokrateio, National and Kapodistrian University of Athens Athens Greece.
Aristeidis AndroulakisState Department of Cardiology General Hospital of Athens Ippokrateio Athens Greece.
Dimitrios TousoulisFirst Department of Cardiology General Hospital of Athens Ippokrateio, National and Kapodistrian University of Athens Athens Greece.
National and Kapodistrian University of Athens · GRIppokrateio General Hospital of Thessaloniki · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe majority of beta thalassemia major (β-TM) patients suffer from cardiac disease, while a significant proportion of them die suddenly. Twelve-lead and signal-averaged electrocardiography (SAECG) are simple, inexpensive, readily available tools for identifying an unfavorable arrhythmiological substrate by detecting the presence of arrhythmias, conduction abnormalities, and late potentials (LPs) in these patients.

methodsA total of 47 β-TM patients and 30 healthy controls were submitted to 12-lead and signal-averaged electrocardiography. Basic electrocardiographic parameters and prevalence of LPs were recorded. Basic echocardiographic parameters were estimated by transthoracic echocardiography. T2* was calculated by cardiac magnetic resonance imaging wherever available.

resultsβ-TM patients demonstrated a more prolonged PR interval (167.74 msec vs 147.07 msec) (

conclusionsβ-TM patients have a higher prevalence of a prolonged PR interval, atrial fibrillation, and LPs. Twelve-lead and SAECG performance was feasible in all subjects and constitutes a readily available tool for assessing myocardial electrophysiological alterations in this patient group.

Indexed as

beta thalassemialate potentialsrisk stratificationsignal‐averaged ECGsudden cardiac death

Identifiers

PMID33024470
PMCPMC7532271
OpenAlexW3045198904

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.