Evidence map›Paper›PMID 33024439›Full record

ArticleFrontiers in genetics2020

Genetic Analysis of Antibody Response to Porcine Reproductive and Respiratory Syndrome Vaccination as an Indicator Trait for Reproductive Performance in Commercial Sows.

Leticia P Sanglard, Rohan L Fernando, Kent A Gray, Daniel C L Linhares, Jack C M Dekkers, Megan C Niederwerder, Nick V L Serão

Open access · goldAbstract read
In one paragraph

Article in Frontiers in genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
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  5. Sequence variants associated with resilient responses in growing pigs.Journal of animal breeding and genetics = Zeitschrift fur Tierzuchtung und Zuchtungsbiologie · 2025
    Article
  6. Selection for Resilience in Livestock Production Systems.International journal of molecular sciences · 2024
    Review
  7. Article
  8. A genome-wide screen for resilient responses in growing pigs.Genetics, selection, evolution : GSE · 2022
    Article
  9. Article
  10. Article
  11. Review: Livestock disease resilience: from individual to herd level.Animal : an international journal of animal bioscience · 2021
    Review
  12. Article
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Leticia P SanglardDepartment of Animal Science, Iowa State University, Ames, IA, United States.
Rohan L FernandoDepartment of Animal Science, Iowa State University, Ames, IA, United States.
Kent A GraySmithfield Premium Genetics, Rose Hill, NC, United States.
Daniel C L LinharesDepartment of Veterinary Diagnostic and Production Animal Medicine, Iowa State University, Ames, IA, United States.
Jack C M DekkersDepartment of Animal Science, Iowa State University, Ames, IA, United States.
Megan C NiederwerderDepartment of Diagnostic Medicine/Pathobiology, Kansas State University, Manhattan, KS, United States.
Nick V L SerãoDepartment of Animal Science, Iowa State University, Ames, IA, United States.
Iowa State University · USKansas State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We proposed to investigate the genomic basis of antibody response to porcine reproductive and respiratory syndrome (PRRS) virus (PRRSV) vaccination and its relationship to reproductive performance in non-PRRSV-infected commercial sows. Nine hundred and six F1 replacement gilts (139 ± 17 days old) from two commercial farms were vaccinated with a commercial modified live PRRSV vaccine. Blood samples were collected about 52 days after vaccination to measure antibody response to PRRSV as sample-to-positive (S/P) ratio and for single-nucleotide polymorphism (SNP) genotyping. Reproductive performance was recorded for up to 807 sows for number born alive (NBA), number of piglets weaned, number born mummified (MUM), number of stillborn (NSB), and number of pre-weaning mortality (PWM) at parities (P) 1-3 and per sow per year (PSY). Fertility traits such as farrowing rate and age at first service were also analyzed. BayesC0 was used to estimate heritability and genetic correlations of S/P ratio with reproductive performance. Genome-wide association study (GWAS) and genomic prediction were performed using BayesB. The heritability estimate of S/P ratio was 0.34 ± 0.05. High genetic correlations (

Indexed as

antibody responsebivariate genome-wide association studygenetic correlationheritabilityporcine reproductive and respiratory syndrome vaccinationreproductive performance

Identifiers

PMID33024439
PMCPMC7516203
OpenAlexW3085250390

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.