Evidence map›Paper›PMID 33024217›Full record

ArticleScientific reports2020

Fatty acid-binding protein 5 limits ILC2-mediated allergic lung inflammation in a murine asthma model.

Shuhei Kobayashi, Shunichi Tayama, Hai The Phung, Yoshiteru Kagawa, Hirofumi Miyazaki, Yu Takahashi, Takashi Maruyama, Naoto Ishii, Yuji Owada

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. FABP5 regulates ether lipid metabolism to ameliorate atopic dermatitis.bioRxiv : the preprint server for biology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Shuhei Kobayashi *Department of Organ Anatomy, Tohoku University Graduate School of Medicine, Sendai, 980-8575, Japan. s_kobayashi@med.tohoku.ac.jp.
Shunichi Tayama *Department of Microbiology and Immunology, Tohoku University Graduate School of Medicine, Sendai, 980-8575, Japan.
Hai The PhungDepartment of Microbiology and Immunology, Tohoku University Graduate School of Medicine, Sendai, 980-8575, Japan.
Yoshiteru KagawaDepartment of Organ Anatomy, Tohoku University Graduate School of Medicine, Sendai, 980-8575, Japan.
Hirofumi MiyazakiDepartment of Organ Anatomy, Tohoku University Graduate School of Medicine, Sendai, 980-8575, Japan.
Yu TakahashiDepartment of Organ Anatomy, Tohoku University Graduate School of Medicine, Sendai, 980-8575, Japan.
Takashi MaruyamaMucosal Immunology Unit, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD, 20895, USA.
Naoto IshiiDepartment of Microbiology and Immunology, Tohoku University Graduate School of Medicine, Sendai, 980-8575, Japan.
Yuji OwadaDepartment of Organ Anatomy, Tohoku University Graduate School of Medicine, Sendai, 980-8575, Japan. owada@med.tohoku.ac.jp.
Tohoku University · JPNational Institute of Dental and Craniofacial Research · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dietary obesity is regarded as a problem worldwide, and it has been revealed the strong linkage between obesity and allergic inflammation. Fatty acid-binding protein 5 (FABP5) is expressed in lung cells, such as alveolar epithelial cells (ECs) and alveolar macrophages, and plays an important role in infectious lung inflammation. However, we do not know precise mechanisms on how lipid metabolic change in the lung affects allergic lung inflammation. In this study, we showed that Fabp5

Indexed as

Alveolar Epithelial CellsAnimalsAsthmaDiet, High-FatDisease Models, AnimalFatty Acid-Binding ProteinsGene ExpressionInflammationInterleukin-1 Receptor-Like 1 ProteinLipid MetabolismLungLymphocytesMice, Inbred C57BLMolecular Targeted TherapyNeoplasm ProteinsObesityFabp5 protein, mouseFatty Acid-Binding ProteinsIl1rl1 protein, mouseInterleukin-1 Receptor-Like 1 ProteinNeoplasm ProteinsTretinoin

Identifiers

PMID33024217
PMCPMC7538993
OpenAlexW3092427262

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.