ArticleScientific reports2020
Heavy metal pollution and risk assessment by the battery of toxicity tests.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 77 citations in OpenAlex.
- Fate and Effects of Heavy Metals in Fishes: Antioxidant Defense System, miRNA/Gene Expression Response, and Histopathological Reproductive Manifestations.Biological trace element research · 2025Review
- Polypyrrole Solid-State Supercapacitors Drawn on Paper.Nanomaterials (Basel, Switzerland) · 2023Article
- Seasonal assessment of selected trace elements in grass carp (Ctenopharyngodon idella) blood and their effects on the biochemistry and oxidative stress markers.Environmental monitoring and assessment · 2023Article
- Heavy metal toxicity arising from the industrial effluents repercussions on oxidative stress, liver enzymes and antioxidant activity in brain homogenates of Oreochromis niloticus.Scientific reports · 2023Article
- Recent Advances in the Treatment of Industrial Wastewater from Different Celluloses in Continuous Systems.Polymers · 2023Review
- Internal Defense System ofToxics · 2023Article
- Lamellar Graphene Oxide-Based Composite Membranes for Efficient Separation of Heavy Metal Ions and Desalination of Water.ACS omega · 2023Article
- Bagarius bagarius, and Eichhornia crassipes are suitable bioindicators of heavy metal pollution, toxicity, and risk assessment.Scientific reports · 2023Article
- Review
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- Water Hardness Can Reduce the Accumulation and Oxidative Stress of Zinc in Goldfish,Antioxidants (Basel, Switzerland) · 2022Article
- Are Ayurvedic medications store house of heavy metals?Toxicology research · 2022Article
- Water quality index,Saudi journal of biological sciences · 2022Article
- Heavy metals content in ashes of wood pellets and the health risk assessment related to their presence in the environment.Scientific reports · 2021Article
- Multibiomarker responses to polycyclic aromatic hydrocarbons and microplastics in thumbprint emperor Lethrinus harak from a South Pacific locally managed marine area.Scientific reports · 2021Article
- Bioaccumulation of heavy metals and their toxicity assessment inSaudi journal of biological sciences · 2021Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The current study was carried out on dominant fish Oreochromis niloticus and water collected from the polluted Yamuna River, Agra, India. The heavy metals in water, recorded as follows: Fe > Mn > Zn > Cu > Ni > Cr > Cd and all were found to be above the prescribed limits. According to metal pollution index, exposed muscle (49.86), kidney (47.68) and liver (45.26) have been recorded to have higher bioaccumulation. The blood biochemical analysis of exposed O. niloticus indicated significant increase in activities of aspartate aminotransferase (+ 343.5%), alkaline phosphatase (+ 673.6%), alanine aminotransferase (+ 309.1%), and creatinine (+ 494.3%) over the reference. However, a significant decrease in albumin (A): globulins (G) ratio (- 87.86%) was observed. Similarly, the exposed fish also showed significant increase in total leucocyte count (+ 121%), differential leucocyte count, respiratory burst (+ 1175%), and nitric oxide synthase (+ 420%). The histological examination of liver and kidney showed tissue injury. Moreover, micronuclei (0.95%), kidney shaped nuclei (1.2%), and lobed nuclei (0.6%) along with DNA damage in the form of mean tail length in the liver (20.7 µm) and kidney (16.5 µm) was observed in the exposed O. niloticus. Potential health risk assessments based on estimated daily intake, target hazard quotient, hazard index, and target cancer risk indicated health risks associated with the consumption of these contaminated fishes. In conclusion, the present study showed that exposure to heavy metals contaminated water can alter immunological response; induce histopathological alterations and DNA damage in the studied fish. The consumption of this contaminated water or fish could have serious impact on human health.
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