Evidence map›Paper›PMID 33024030›Full record

ArticlemBio2020

Phosphorylation of Rhoptry Protein RhopH3 Is Critical for Host Cell Invasion by the Malaria Parasite.

Roseleen Ekka, Ankit Gupta, Sonika Bhatnagar, Pawan Malhotra, Pushkar Sharma

Open access · goldAbstract read
In one paragraph

Article in mBio, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
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  10. Identification and Characterization ofVeterinary sciences · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Roseleen Ekka *Eukaryotic Gene Expression Laboratory, National Institute of Immunology, New Delhi, India.
Ankit Gupta *Eukaryotic Gene Expression Laboratory, National Institute of Immunology, New Delhi, India.
Sonika BhatnagarEukaryotic Gene Expression Laboratory, National Institute of Immunology, New Delhi, India.
Pawan MalhotraInternational Center for Genetic Engineering and Biotechnology, New Delhi, India.
Pushkar SharmaEukaryotic Gene Expression Laboratory, National Institute of Immunology, New Delhi, India pushkar@nii.ac.in.ORCID 0000-0001-6861-0508
National Institute of Immunology · INInternational Centre for Genetic Engineering and Biotechnology · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Merozoites formed after asexual division of the malaria parasite invade the host red blood cells (RBCs), which is critical for initiating malaria infection. The process of invasion involves specialized organelles like micronemes and rhoptries that discharge key proteins involved in interaction with host RBC receptors. RhopH complex comprises at least three proteins, which include RhopH3. RhopH3 is critical for the process of red blood cell (RBC) invasion as well as intraerythrocytic development of human malaria parasite

Indexed as

ErythrocytesHost-Parasite InteractionsHumansMalaria, FalciparumMerozoitesPhosphorylationPlasmodium falciparumProtozoan ProteinsProtozoan Proteinshost cell invasioninvasionmalariaphosphorylationprotein phosphorylationsignaling

Identifiers

PMID33024030
PMCPMC7542355
OpenAlexW3092107956

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.