Evidence map›Paper›PMID 33023987›Full record

ArticleDiabetes care2020

Glycemic Control and the Risk of Acute Kidney Injury in Patients With Type 2 Diabetes and Chronic Kidney Disease: Parallel Population-Based Cohort Studies in U.S. and Swedish Routine Care.

Yang Xu, Aditya Surapaneni, Jim Alkas, Marie Evans, Jung-Im Shin, Elizabeth Selvin, Alex Chang, Morgan E Grams, Juan Jesus Carrero

Open access · bronzeAbstract read
In one paragraph

Article in Diabetes care, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
  2. Article
  3. Observational
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  5. Article
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  10. Long-term Visit-to-Visit Variability in Hemoglobin AAmerican journal of kidney diseases : the official journal of the National Kidney Foundation · 2023
    Observational
  11. Acute kidney injury in diabetes mellitus: Epidemiology, diagnostic, and therapeutic concepts.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2023
    Review
  12. Article
  13. Article
  14. Impact of Diabetes on the Recurrence and Prognosis of Acute Kidney Injury in Older Male Patients: A 10-Year Retrospective Cohort Study.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2022
    Article
  15. Article
  16. Article
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  18. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Yang XuMedical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden yang.xu@ki.se juan.jesus.carrero@ki.se.ORCID 0000-0002-1074-608X
Aditya SurapaneniDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD.
Jim AlkasMedical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Marie EvansDivision of Renal Medicine, Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden.
Jung-Im ShinDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD.ORCID 0000-0003-0374-6927
Elizabeth SelvinDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD.ORCID 0000-0001-6923-7151
Alex ChangDivision of Nephrology, Geisinger Health System, Danville, PA.
Morgan E GramsDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD.ORCID 0000-0002-4430-6023
Juan Jesus CarreroMedical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden yang.xu@ki.se juan.jesus.carrero@ki.se.ORCID 0000-0003-4763-2024
Johns Hopkins University · USKarolinska Institutet · SEGeisinger Health System · US

Funding

Chronic Kidney Disease Prognosis Consortium (CKD-PC)R01DK100446 · NIDDK · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI JOSEF CORESH, Morgan Erika Grams · 2014 to 2026
$10.7M
Medication Use and Adverse Events in CKDR01DK115534 · NIDDK · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Alexander R Chang, Morgan Erika Grams · 2018 to 2026
$5.7M
Research and Mentoring in the Clinical Epidemiology of Type 2 DiabetesK24DK106414 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI SELVIN, ELIZABETH · 2015 to 2019
$654k
The Comparative Effectiveness and Safety of Second-line Therapy in Patients with Type 2 DiabetesK01DK121825 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI SHIN, JUNG-IM · 2019 to 2022
$615k
Research and Mentoring in the Clinical Epidemiology of Cardiovascular Disease and Type 2 DiabetesK24HL152440 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI SELVIN, ELIZABETH · 2020 to 2024
$612k
NHLBI NIH HHS K24 HL152440NIDDK NIH HHS K01 DK121825NIDDK NIH HHS K24 DK106414NIDDK NIH HHS R01 DK100446NIDDK NIH HHS R01 DK115534
6 · The paper itself

Abstract

objectivePatients with diabetes and chronic kidney disease (CKD) have increased susceptibility to acute kidney injury (AKI), but mechanisms are unclear. We investigated the association of glycemic control with risk of AKI. RESEARCH DESIGN AND

methodsIn two observational cohorts of U.S. (Geisinger Health System, Danville, PA) and Swedish (Stockholm CREAtinine Measurements [SCREAM] project, Stockholm, Sweden) adults with type 2 diabetes and confirmed CKD stages G3-G5 undergoing routine care, we evaluated associations between baseline and time-varying hemoglobin A

resultsIn the U.S. cohort, there were 22,877 patients (55% women) with a median age of 72 years and estimated glomerular filtration rate (eGFR) 52 mL/min/1.73 m

conclusionsHigher HbA

Indexed as

Acute Kidney InjuryAgedCohort StudiesCreatinineDiabetes Mellitus, Type 2FemaleGlomerular Filtration RateGlycated HemoglobinGlycemic ControlHumansMaleRenal Insufficiency, ChronicSwedenUnited StatesCreatinineGlycated Hemoglobin

Identifiers

PMID33023987
PMCPMC7770276
OpenAlexW3091991482

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.