ReviewJournal of neuroinflammation2020
The effect of insomnia on development of Alzheimer's disease.
Review in Journal of neuroinflammation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
60 citing papers in PubMed, 2 syntheses or guidelines pooled it, 102 citations in OpenAlex.
- Imbalanced sleep increases mortality risk by 14-34%: a meta-analysis.GeroScience · 2025Pooled it
- Brain Functional and Structural Changes in Alzheimer's Disease With Sleep Disorders: A Systematic Review.Frontiers in psychiatry · 2021Pooled it
- Cognitive status moderates long-term benefits of non-pharmacological insomnia therapy in older adults: A secondary analysis of a randomized clinical trial.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Trial
- Insomnia symptoms and stress exposure interact in relation to Alzheimer's disease biomarkers.Journal of neurology · 2026Article
- The combined association between sleep duration and insomnia symptoms with dementia and cognitive deficits: a multivariable-adjusted and genetic liability study.GeroScience · 2026Article
- Dynamic thermodynamic-informational entropic relationship (TIER) models of selective vulnerability to neurodegeneration.bioRxiv : the preprint server for biology · 2026Article
- Sleep disturbances and Alzheimer's disease: a multiscale approach from exposome to neurobiology and precision medicine.GeroScience · 2026Review
- Co-Developing a Culturally Responsive, Theory-Informed Dyadic Mind-Body Intervention to Improve Sleep and Wellbeing in People with Dementia and Their Caregivers in the UK.Healthcare (Basel, Switzerland) · 2026Article
- Handcrafted MRI radiomics of enlarged perivascular spaces and machine learning predict cognitive impairment and sleep disturbance in young adults.Scientific reports · 2026Article
- Cognitive training at home for clinically defined insomnia: effects on sleep and psychological functioning.Frontiers in digital health · 2026Article
- The Effect of Dry Needling on Sleep Quality in Individuals With Musculoskeletal Pain Disorders.Pain research & management · 2026Review
- Listening to voices across cultures: non-pharmacological approaches to coping with sleep problems in dementia among ethnically diverse older adults in the UK.BMC complementary medicine and therapies · 2025Article
- Melatonin Supplementation in Alzheimer's disease: The Potential Role in Neurogenesis.Molecular neurobiology · 2025Review
- Association between longitudinal trajectories of insomnia symptoms and subsequent cognitive decline: a prospective cohort study.Age and ageing · 2025Article
- MicroRNAs modulation by curcumin, catalpol, and other natural products in Alzheimer's disease: a review.Molecular biology reports · 2025Review
- Mapping the Neural Basis of Wake Onset Regularity and Its Effects on Sleep Quality and Positive Affect.Clocks & sleep · 2025Article
- Transcriptomics and network pharmacology reveal the molecular mechanisms through which leonurine protects againstFrontiers in microbiology · 2025Article
- Study on the relationship between insomnia disorder, PET/CT, and gut microbiota in patients with Alzheimer's disease.Frontiers in neurology · 2025Article
- A valuation based theory of learning's origin and development.Frontiers in systems neuroscience · 2025Article
- An examination into the effects of tocotrienols (TheraPrimE® rice) on cognitive abilities and sleep in healthy adults: a randomised, double-blind, placebo-controlled trial.Frontiers in nutrition · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Alzheimer's disease (AD) is the most common type of dementia and a neurodegenerative disorder characterized by memory deficits especially forgetting recent information, recall ability impairment, and loss of time tracking, problem-solving, language, and recognition difficulties. AD is also a globally important health issue but despite all scientific efforts, the treatment of AD is still a challenge. Sleep has important roles in learning and memory consolidation. Studies have shown that sleep deprivation (SD) and insomnia are associated with the pathogenesis of Alzheimer's disease and may have an impact on the symptoms and development. Thus, sleep disorders have decisive effects on AD; this association deserves more attention in research, diagnostics, and treatment, and knowing this relation also can help to prevent AD through screening and proper management of sleep disorders. This study aimed to show the potential role of SD and insomnia in the pathogenesis and progression of AD.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.