Evidence map›Paper›PMID 33023332›Full record

ReviewExperimental biology and medicine (Maywood, N.J.)2021

Attenuation of acute and chronic inflammation using compounds derived from plants.

Stephen C Bondy, Meixia Wu, Kedar N Prasad

Open access · greenAbstract readReview
In one paragraph

Review in Experimental biology and medicine (Maywood, N.J.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Stephen C BondyCenter for Occupational and Environmental Health, University of California, Irvine, CA 92697, USA.ORCID 0000-0001-5158-2993
Meixia WuCenter for Occupational and Environmental Health, University of California, Irvine, CA 92697, USA.
Kedar N PrasadEngage Global, San Rafael, CA 94903, USA.ORCID 0000-0001-5128-0063
University of California, Irvine · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The appearance of excessive inflammatory activity is associated with onset of many disease states. Such non-productive responses are often the basis of the mortality consequent to incurring numerous disorders. The current outbreak of coronavirus disease 2019 caused by the virus "severe acute respiratory syndrome coronavirus 2" is a striking reflection of the inadequacy of current medical science to adequately address this issue. The usefulness of a range of materials of botanical origin in the attenuation of both chronic and acute inflammatory responses to various disease stressors is described. The properties of preparations of plant-based origin often parallel those of synthesized pharmacologics, but differ from them in some key respects. These differences can lead to more traditional preparations having distinct therapeutic advantages but also a number of specific shortcomings. The strengths and weaknesses of these materials are objectively contrasted with that of a more orthodox pharmacological approach. Each of these emphases in style has specific advantages and they should not be considered as competitors, but rather as accomplices in combating adverse states involving derangement of immune function.

Indexed as

COVID-19 Drug TreatmentCytokinesHumansInflammationNF-kappa BNitric Oxide Synthase Type IIPhytochemicalsPlant PreparationsSARS-CoV-2Tumor Necrosis Factor-alphaCytokinesNF-kappa BNitric Oxide Synthase Type IINOS2 protein, humanPhytochemicalsPlant PreparationsTNF protein, humanTumor Necrosis Factor-alphaInflammationinflammatory cytokinesoxidative stressSARS-CoV-2 virussignaling pathways

Identifiers

PMID33023332
PMCPMC7885045
OpenAlexW3092411305

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.