Evidence map›Paper›PMID 33023296›Full record

ArticleAutism : the international journal of research and practice2021

How do core autism traits and associated symptoms relate to quality of life? Findings from the Longitudinal European Autism Project.

Bethany Fm Oakley, Julian Tillmann, Jumana Ahmad, Daisy Crawley, Antonia San José Cáceres, Rosemary Holt, Tony Charman, Tobias Banaschewski, Jan Buitelaar, Emily Simonoff and 2 more

Abstract read
In one paragraph

Article in Autism : the international journal of research and practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
76citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

76 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Quality of life in adults with autism spectrum disorder: influence of age, sex, and a controlled, randomized mindfulness-based stress reduction pilot intervention.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022
    Trial
  7. Article
  8. Article
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  11. Variability in sensory processing and evoked potentials in Rett syndrome.medRxiv : the preprint server for health sciences · 2026
    Article
  12. Article
  13. Review
  14. Article
  15. Autistic young people's psychological well-being in school.Autism : the international journal of research and practice · 2026
    Article
  16. Article
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  18. Article
  19. Article
  20. Article

16 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Bethany Fm OakleyKing's College London, UK.ORCID 0000-0002-1968-134X
Julian TillmannKing's College London, UK.
Jumana AhmadKing's College London, UK.
Daisy CrawleyKing's College London, UK.
Antonia San José CáceresKing's College London, UK.
Rosemary HoltUniversity of Cambridge, UK.
Tony CharmanKing's College London, UK.ORCID 0000-0003-1993-6549
Tobias BanaschewskiUniversität Mannheim, Germany.ORCID 0000-0003-4595-1144
Jan BuitelaarRadboud University Nijmegen Medical Center, The Netherlands.
Emily SimonoffKing's College London, UK.ORCID 0000-0002-5450-0823
Declan MurphyKing's College London, UK.
Eva LothKing's College London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

lay abstractPrevious studies suggest that some autistic individuals report lower satisfaction, or well-being, with different aspects of everyday life than those without autism. It is unclear whether this might be partly explained by symptoms of anxiety and/or depression, which affect at least 20%-50% of autistic people. In this study, we measured individual differences in well-being in 573 six to thirty-year-olds with and without a diagnosis of autism. We investigated whether individual differences in well-being were explained by autism traits (e.g. social-communication difficulties) and/or anxiety and depression symptoms. We showed that, though well-being was lower for some autistic individuals, compared to those without autism, many autistic individuals reported good well-being. Where well-being was reduced, this was particularly explained by depression symptoms, across all ages. For children/adolescents, anxiety and social-communication difficulties were also related to some aspects of well-being. Our study suggests that support and services for improving mental health, especially depression symptoms, may also improve broader outcomes for autistic people.

Indexed as

Autism Spectrum DisorderAutistic DisorderAdolescentAnxiety DisordersChildHumansPersonal SatisfactionQuality of Lifeanxietyautismdepressionquality of lifewell-being

Identifiers

PMID33023296
PMCPMC7874383

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.