Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literature
Who cites it
1 citing paper in PubMed, 3 citations in OpenAlex.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
7 authors at 4 institutions in 2 countries.
Maria Giulia DavighiDepartment of Chemistry "Ugo Schiff", University of Firenze, via della Lastruccia 3-13, 50019 Sesto Fiorentino, Italy.
Francesca ClementeDepartment of Chemistry "Ugo Schiff", University of Firenze, via della Lastruccia 3-13, 50019 Sesto Fiorentino, Italy.
Camilla MatassiniDepartment of Chemistry "Ugo Schiff", University of Firenze, via della Lastruccia 3-13, 50019 Sesto Fiorentino, Italy.ORCID 0000-0002-6766-4624
Amelia MorronePaediatric Neurology Unit and Laboratories, Neuroscience Department, Meyer Children's Hospital, and Department of Neurosciences, Pharmacology and Child Health. University of Florence, Viale Pieraccini 24, 50139 Firenze, Italy.ORCID 0000-0003-2890-8179
Andrea GotiDepartment of Chemistry "Ugo Schiff", University of Firenze, via della Lastruccia 3-13, 50019 Sesto Fiorentino, Italy.
Macarena Martínez-BailénDepartamento de Química Orgánica, Facultad de Química, Universidad de Sevilla, García González 1, E-41012 Sevilla, Spain.
Francesca CardonaDepartment of Chemistry "Ugo Schiff", University of Firenze, via della Lastruccia 3-13, 50019 Sesto Fiorentino, Italy.ORCID 0000-0002-8336-383X
University of Florence · ITConsorzio Interuniversitario Reattività Chimica e Catalisi · ITMeyer Children's Hospital · ITUniversidad de Sevilla · ES
Funding
Cassa di Risparmio di Pistoia e Pescia Bando Giovani@Ricerca scientifica 2017Fondazione CR Firenze Bando congiunto per il finanziamento di progetti competitivi sulle malattie neurodegenerative. Project: A multidisciplinary approach to target Parkinson's disease in Gaucher related population, Acronym: MuTaParGaFondazione CR Firenze grant N°2018.0942Fondazione CR Firenze grant number 2017.0734Ministerio de Economía y Competitividad of Spain CTQ2016-77270-RRegione Toscana (Bando Salute 2018) "Late onset Lysosomal Storage Disorders (LSDs) in the differential diagnosis of neurodegenerative diseases: development of new diagnostic procedures and focus on potential pharmacological chaperones (PCs), Acronym: Lysolate
6 · The paper itself
Abstract
Pharmacological chaperones (PCs) are small compounds able to rescue the activity of mutated lysosomal enzymes when used at subinhibitory concentrations. Nitrogen-containing glycomimetics such as aza- or iminosugars are known to behave as PCs for lysosomal storage disorders (LSDs). As part of our research into lysosomal sphingolipidoses inhibitors and looking in particular for new β-galactosidase inhibitors, we report the synthesis of a series of alkylated azasugars with a relative "
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.