Evidence map›Paper›PMID 33023127›Full record

ArticleAntioxidants (Basel, Switzerland)2020

Molecular Characterization, Protein-Protein Interaction Network, and Evolution of Four Glutathione Peroxidases from

Diana Ferro, Rigers Bakiu, Sandra Pucciarelli, Cristina Miceli, Adriana Vallesi, Paola Irato, Gianfranco Santovito

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Nutritional Support: The Use of Antioxidants in Inflammatory Bowel Disease.International journal of molecular sciences · 2024
    Review
  3. Article
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  11. PFAS Environmental Pollution and Antioxidant Responses: An Overview of the Impact on Human Field.International journal of environmental research and public health · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Diana FerroBIO5 Institute, University of Arizona, Tucson, AZ 85719, USA.
Rigers BakiuDepartment of Aquaculture and Fisheries, Agricultural University of Tirana, 1000 Tiranë, Albania.ORCID 0000-0002-9613-4606
Sandra PucciarelliSchool of Biosciences and Veterinary Medicine, University of Camerino, 62032 Camerino, Italy.
Cristina MiceliSchool of Biosciences and Veterinary Medicine, University of Camerino, 62032 Camerino, Italy.ORCID 0000-0002-7829-8471
Adriana VallesiSchool of Biosciences and Veterinary Medicine, University of Camerino, 62032 Camerino, Italy.ORCID 0000-0002-4127-090X
Paola IratoDepartment of Biology, University of Padova, 35131 Padova, Italy.
Gianfranco SantovitoDepartment of Biology, University of Padova, 35131 Padova, Italy.ORCID 0000-0001-8260-7006
Università di Camerino · ITUniversity of Padua · ITAgricultural University of Tirana · ALChildren's Mercy Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glutathione peroxidases (GPxs) form a broad family of antioxidant proteins essential for maintaining redox homeostasis in eukaryotic cells. In this study, we used an integrative approach that combines bioinformatics, molecular biology, and biochemistry to investigate the role of GPxs in reactive oxygen species detoxification in the unicellular eukaryotic model organism

Indexed as

antioxidant systemciliate protistscopperfree-radicalsglutathione peroxidases genesGPxmetalsprotein–protein interaction networkreactive oxygen speciesROS

Identifiers

PMID33023127
PMCPMC7600574
OpenAlexW3083299533

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.