Evidence map›Paper›PMID 33023047›Full record

ReviewPathogens (Basel, Switzerland)2020

Roles of the Non-Structural Proteins of Influenza A Virus.

Wenzhuo Hao, Lingyan Wang, Shitao Li

Open access · goldAbstract readReview
In one paragraph

Review in Pathogens (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 48 citations in OpenAlex.

  1. Review
  2. Article
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  5. The strategies and advances of mRNA translation booster.Asian journal of pharmaceutical sciences · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Wenzhuo HaoDepartment of Microbiology and Immunology, Tulane University, New Orleans, LA 70118, USA.
Lingyan WangDepartment of Microbiology and Immunology, Tulane University, New Orleans, LA 70118, USA.
Shitao LiDepartment of Microbiology and Immunology, Tulane University, New Orleans, LA 70118, USA.
Tulane University · US

Funding

Role of FIP200 in RIG-I-mediated innate immunityR01AI141399 · NIAID · TULANE UNIVERSITY OF LOUISIANA · PI LI, SHITAO · 2019 to 2023
$1.7M
Regulation of cGAS-Mediated Cytosolic DNA Sensing PathwayR21AI137750 · NIAID · TULANE UNIVERSITY OF LOUISIANA · PI LI, SHITAO · 2018 to 2019
$413k
NIAID NIH HHS R01 AI141399NIAID NIH HHS R21 AI137750NIH HHS R01AI141399NIH HHS R21AI137750
6 · The paper itself

Abstract

Influenza A virus (IAV) is a segmented, negative single-stranded RNA virus that causes seasonal epidemics and has a potential for pandemics. Several viral proteins are not packed in the IAV viral particle and only expressed in the infected host cells. These proteins are named non-structural proteins (NSPs), including NS1, PB1-F2 and PA-X. They play a versatile role in the viral life cycle by modulating viral replication and transcription. More importantly, they also play a critical role in the evasion of the surveillance of host defense and viral pathogenicity by inducing apoptosis, perturbing innate immunity, and exacerbating inflammation. Here, we review the recent advances of these NSPs and how the new findings deepen our understanding of IAV-host interactions and viral pathogenesis.

Indexed as

influenzainnate immunitynon-structural proteinNS1PA-XPB1-F2virulence

Identifiers

PMID33023047
PMCPMC7600879
OpenAlexW3090052825

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.