Evidence map›Paper›PMID 33023024›Full record

ReviewInternational journal of molecular sciences2020

Drug Development and the Use of Induced Pluripotent Stem Cell-Derived Cardiomyocytes for Disease Modeling and Drug Toxicity Screening.

Paz Ovics, Danielle Regev, Polina Baskin, Mor Davidor, Yuval Shemer, Shunit Neeman, Yael Ben-Haim, Ofer Binah

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 28 citations in OpenAlex.

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  17. hiPSC-Derived Cells as Models for Drug Discovery.International journal of molecular sciences · 2021
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  19. Silencing ofInternational journal of molecular sciences · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Paz OvicsDepartment of Physiology, Biophysics and Systems Biology, The Rappaport Institute, Ruth & Bruce Rappaport Faculty of Medicine, Technion, Haifa 31096, Israel.
Danielle RegevDepartment of Physiology, Biophysics and Systems Biology, The Rappaport Institute, Ruth & Bruce Rappaport Faculty of Medicine, Technion, Haifa 31096, Israel.
Polina BaskinDepartment of Physiology, Biophysics and Systems Biology, The Rappaport Institute, Ruth & Bruce Rappaport Faculty of Medicine, Technion, Haifa 31096, Israel.
Mor DavidorDepartment of Physiology, Biophysics and Systems Biology, The Rappaport Institute, Ruth & Bruce Rappaport Faculty of Medicine, Technion, Haifa 31096, Israel.
Yuval ShemerDepartment of Physiology, Biophysics and Systems Biology, The Rappaport Institute, Ruth & Bruce Rappaport Faculty of Medicine, Technion, Haifa 31096, Israel.
Shunit NeemanDepartment of Physiology, Biophysics and Systems Biology, The Rappaport Institute, Ruth & Bruce Rappaport Faculty of Medicine, Technion, Haifa 31096, Israel.
Yael Ben-HaimInstitute of Molecular and Clinical Sciences, St. George's University of London, London SW17 0RE, UK.
Ofer BinahDepartment of Physiology, Biophysics and Systems Biology, The Rappaport Institute, Ruth & Bruce Rappaport Faculty of Medicine, Technion, Haifa 31096, Israel.
Rappaport Family Institute for Research in the Medical Sciences · ILSt George's, University of London · GB

Funding

The state of Lower-Saxony and the Volkswagen Foundation, Hannover, Germany 2020591
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CardiotoxicityCell DifferentiationDrug Evaluation, PreclinicalDrug-Related Side Effects and Adverse ReactionsHeart DiseasesHumansInduced Pluripotent Stem CellsMyocytes, CardiacAdverse Drug Reactions (ADRs)cardiotoxiciychannelopathiesdrug screeningiPSC-CMslaminopathiesmetabolic mutationsstructural mutations

Identifiers

PMID33023024
PMCPMC7582587
OpenAlexW3090916670

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.