Evidence map›Paper›PMID 33023010›Full record

ArticleCells2020

Sex Differences in Diabetes- and TGF-β1-Induced Renal Damage.

Nadja Ziller, Roland Kotolloshi, Mohsen Esmaeili, Marita Liebisch, Ralf Mrowka, Aria Baniahmad, Thomas Liehr, Gunter Wolf, Ivonne Loeffler

Open access · goldAbstract read
In one paragraph

Article in Cells, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Features of the Therapy of Liver Cirrhosis in Aged Male and Female Rats.Bulletin of experimental biology and medicine · 2025
    Article
  9. The Role of Estrogen across Multiple Disease Mechanisms.Current issues in molecular biology · 2024
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Observational
  17. Role of sex hormones in diabetic nephropathy.Frontiers in endocrinology · 2023
    Review
  18. Review
  19. Article
  20. Effect of Sex Differences in Silicotic Mice.International journal of molecular sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Nadja ZillerDepartment of Internal Medicine III, Jena University Hospital, Am Klinikum 1, D-07747 Jena, Germany.
Roland KotolloshiInstitute of Human Genetics, Jena University Hospital, Am Klinikum 1, D-07747 Jena, Germany.
Mohsen EsmaeiliInstitute of Human Genetics, Jena University Hospital, Am Klinikum 1, D-07747 Jena, Germany.
Marita LiebischDepartment of Internal Medicine III, Jena University Hospital, Am Klinikum 1, D-07747 Jena, Germany.
Ralf MrowkaDepartment of Internal Medicine III, Jena University Hospital, Am Klinikum 1, D-07747 Jena, Germany.
Aria BaniahmadInstitute of Human Genetics, Jena University Hospital, Am Klinikum 1, D-07747 Jena, Germany.
Thomas LiehrInstitute of Human Genetics, Jena University Hospital, Am Klinikum 1, D-07747 Jena, Germany.
Gunter WolfDepartment of Internal Medicine III, Jena University Hospital, Am Klinikum 1, D-07747 Jena, Germany.
Ivonne LoefflerDepartment of Internal Medicine III, Jena University Hospital, Am Klinikum 1, D-07747 Jena, Germany.
Jena University Hospital · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While females are less affected by non-diabetic kidney diseases compared to males, available data on sex differences in diabetic nephropathy (DN) are controversial. Although there is evidence for an imbalance of sex hormones in diabetes and hormone-dependent mechanisms in transforming growth factor β1 (TGF-β1) signaling, causes and consequences are still incompletely understood. Here we investigated the influence of sex hormones and sex-specific gene signatures in diabetes- and TGF-β1-induced renal damage using various complementary approaches (a

Indexed as

AnimalsDiabetic NephropathiesDisease Models, AnimalFemaleHumansMaleMiceSex CharacteristicsTransforming Growth Factor beta1TGFB1 protein, humanTransforming Growth Factor beta1DHTdiabetes mellitusdiabetic nephropathyestradiolkidneysex differencestestosteroneTGF-β1transforming growth factor beta 1tubulointerstitial fibrosis

Identifiers

PMID33023010
PMCPMC7600610
OpenAlexW3090750095

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.