Evidence map›Paper›PMID 33022711›Full record

ArticleNephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association2020

Impact of cardiovascular risk stratification strategies in kidney transplantation over time.

Andras T Deak, Francesca Ionita, Alexander H Kirsch, Balazs Odler, Peter P Rainer, Reinhard Kramar, Michael P Kubatzki, Katharina Eberhard, Andrea Berghold, Alexander R Rosenkranz

Open access · hybridAbstract read
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In one paragraph

Article in Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. New kidneys, old risks: cardiovascular challenges after transplantation.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Andras T DeakDepartment of Internal Medicine, Division of Nephrology, Medical University of Graz, Graz, Austria.
Francesca IonitaDepartment of Internal Medicine, Division of Nephrology, Medical University of Graz, Graz, Austria.
Alexander H KirschDepartment of Internal Medicine, Division of Nephrology, Medical University of Graz, Graz, Austria.
Balazs OdlerDepartment of Internal Medicine, Division of Nephrology, Medical University of Graz, Graz, Austria.
Peter P RainerDepartment of Internal Medicine, Division of Cardiology, Medical University of Graz, Graz, Austria.
Reinhard KramarAustrian Dialysis and Transplant Registry, Innsbruck, Austria.
Michael P KubatzkiDepartment of Internal Medicine, Division of Nephrology, Medical University of Graz, Graz, Austria.
Katharina EberhardCore Facility Computational Bioanalytics, Medical University of Graz, Graz, Austria.
Andrea BergholdInstitute for Medical Informatics, Statistics and Documentation, Medical University of Graz, Graz, Austria.
Alexander R RosenkranzDepartment of Internal Medicine, Division of Nephrology, Medical University of Graz, Graz, Austria.
Medical University of Graz · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundKidney transplant recipients exhibit a dramatically increased cardiovascular (CV) risk. In 2007, Austrian centres implemented a consensus of comprehensive CV screening programme prior to kidney transplantation (KT). The consensus placed a particular emphasis on screening for coronary artery disease (CAD) with cardiac computed tomography (CT) or coronary angiography (CAG) in patients with diabetes mellitus, known CAD or those having multiple conventional CV risk factors. Here, we investigate if this affected risk stratification and post-transplant CV outcomes.

methodsIn a retrospective chart review, we evaluated 551 KTs performed from 2003 to 2015 in our centre. Patients were categorized into three groups: KT before (2003-07), directly after (2008-11) and 5 years after (2012-15) implementation of the consensus. We analysed clinical characteristics, the rate of cardiac CTs and CAGs prior to KT as well as major adverse cardiac events (MACEs) during a 2-year follow-up after KT.

resultsThe three study groups showed a homogeneous distribution of comorbidities and age. Significantly more cardiac CTs (13.6% versus 10.2% versus 44.8%; P = 0.002) and CAGs (39.6% versus 43.9% versus 56.2%; P = 0.003) were performed after the consensus. Coronary interventions were performed during 42 out of 260 CAGs (16.2%), the cumulative 2-year MACE incidence was 8.7%. Regarding MACE occurrence, no significant difference between the three groups was found.

conclusionCV risk stratification has become more rigorous and invasive after the implementation of the consensus; however, this was not associated with an improvement in CV outcome.

Indexed as

AdultAustriaCardiovascular DiseasesCoronary AngiographyFemaleHeart Disease Risk FactorsHumansIncidenceKidney TransplantationMaleMiddle AgedRetrospective StudiesRisk AssessmentTime Factorschronic kidney diseasecoronary angiographycoronary artery diseasekidney transplantationmajor adverse cardiac event

Identifiers

PMID33022711
PMCPMC7538198
OpenAlexW3092230742

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.