ArticleJournal of invertebrate pathology2020
Cordycepin, a metabolite of Cordyceps militaris, reduces immune-related gene expression in insects.
Article in Journal of invertebrate pathology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 35 citations in OpenAlex.
- Chemical Conversations.Molecules (Basel, Switzerland) · 2025Review
- Topical Infection of Cordyceps militaris in Silkworm Larvae Through the Cuticle has Lower Infectivity Compared to Beauveria bassiana and Metarhizium anisopliae.Current microbiology · 2024Article
- Immunomodulation and Protective Effects ofInsects · 2024Article
- Application and research progress of cordycepin in the treatment of tumours (Review).Molecular medicine reports · 2024Review
- Entomopathogenic fungi in crops protection with an emphasis on bioactive metabolites and biological activities.World journal of microbiology & biotechnology · 2024Review
- Classification, biology and entomopathogenic fungi-based management and their mode of action againstFrontiers in microbiology · 2024Review
- Research Progress on Cordycepin Synthesis and Methods for Enhancement of Cordycepin Production inBioengineering (Basel, Switzerland) · 2022Review
- Entomotoxic Activity of the Extracts from the Fungus,Journal of fungi (Basel, Switzerland) · 2021Article
- Culture Degeneration Reduces Sex-Related Gene Expression, Alters Metabolite Production and Reduces Insect Pathogenic Response inMicroorganisms · 2021Article
- The Chemical Ecology Approach to Reveal Fungal Metabolites for Arthropod Pest Management.Microorganisms · 2021Review
- Effects of Cordycepin inMicroorganisms · 2021Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Hypocrealean entomopathogenic fungi (EPF) (Sordariomycetes, Ascomycota) are natural regulators of insect populations in terrestrial environments. Their obligately-killing life-cycle means that there is likely to be strong selection pressure for traits that allow them to evade the effects of the host immune system. In this study, we quantified the effects of cordycepin (3'-deoxyadenosine), a secondary metabolite produced by Cordyceps militaris (Hypocreales, Cordycipitaceae), on insect susceptibility to EPF infection and on insect immune gene expression. Application of the immune stimulant curdlan (20 µg ml
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.