Evidence map›Paper›PMID 33022164›Full record

ArticleNeurospine2020

Impact of Nonlordotic Sagittal Alignment on Short-term Outcomes of Cervical Disc Replacement.

Jung Kee Mok, Avani S Vaishnav, Chirag Chaudhary, R Kiran Alluri, Ryan Lee, Hikari Urakawa, Kosuke Sato, Darren A Chen, Catherine Himo Gang, Russel Huang and 2 more

Open access · diamondAbstract read
In one paragraph

Article in Neurospine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Jung Kee MokWeill Cornell Medical College, New York, NY, USA.
Avani S VaishnavHospital for Special Surgery, New York, NY, USA.
Chirag ChaudharyHospital for Special Surgery, New York, NY, USA.
R Kiran AlluriHospital for Special Surgery, New York, NY, USA.
Ryan LeeHospital for Special Surgery, New York, NY, USA.
Hikari UrakawaHospital for Special Surgery, New York, NY, USA.
Kosuke SatoHospital for Special Surgery, New York, NY, USA.
Darren A ChenWeill Cornell Medical College, New York, NY, USA.
Catherine Himo GangHospital for Special Surgery, New York, NY, USA.
Russel HuangWeill Cornell Medical College, New York, NY, USA.
Todd J AlbertWeill Cornell Medical College, New York, NY, USA.
Sheeraz A QureshiWeill Cornell Medical College, New York, NY, USA.
Hospital for Special Surgery · USCornell University · US

Funding

Disparities in COVID Disease Severity and Outcomes in New York CityUL1TR002384 · NCATS · WEILL MEDICAL COLL OF CORNELL UNIV · PI JULIANNE L IMPERATO-MCGINLEY · 2017 to 2026
$86.2M
NCATS NIH HHS UL1 TR002384
6 · The paper itself

Abstract

objectiveTo evaluate outcomes of cervical disc replacement (CDR) in patients with nonlordotic alignment.

methodsPatients who underwent CDR were retrospectively reviewed and divided into 3 cohorts: (1) neutral/lordotic segmental and C2-7 Cobb angle (L), (2) nonlordotic segmental Cobb angle, lordotic C2-7 Cobb angle (NL-S), and (3) nonlordotic segmental and C2-7 Cobb angle (NL-SC). Radiographic and patient-reported outcomes (PROMs) were compared.

resultsOne-hundred five patients were included (L: 37, NL-S: 30, NL-SC: 38). A significant gain in segmental lordosis was seen in all cohorts at < 6 months (L: -1.90° [p = 0.007]; NL-S: -5.16° [p < 0.0001]; NL-SC: -6.00° [p < 0.0001]) and ≥ 6 months (L: -2.07° [p = 0.031; NL-S: -6.04° [p < 0.0001]; NL-SC: -6.74° [p < 0.0001]), with greater lordosis generated in preoperatively nonlordotic cohorts (p < 0.0001). C2-7 lordosis improved in the preoperatively nonlordotic cohort (NL-SC: 8.04°) at follow-up of < 6 months (-4.15°, p = 0.003) and ≥ 6 months (-6.40°, p = 0.003), but not enough to create lordotic alignment (< 6 months: 3.89°; ≥ 6 months: 4.06°). All cohorts showed improvement in Neck Disability Index, visual analogue scale (VAS) neck, and VAS arm, without significant difference among groups in the amount of improvement ( ≥ 6-month PROMs follow-up = 69%).

conclusionIn patients without major kyphotic deformity, CDR has the potential to generate and maintain lordosis and improve PROMs in the short-term, and can be an effective treatment option for patients with nonlordotic alignment.

Indexed as

Cervical alignmentCervical disc replacementNonlordotic alignmentSegmental alignment

Identifiers

PMID33022164
PMCPMC7538348
OpenAlexW3089312201

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.