SynthesisBrain and behavior2020
The changed functional status of the brain was involved in patients with poststroke aphasia: Coordinate-based (activation likelihood estimation) meta-analysis.
Synthesis in Brain and behavior, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.
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Who cites it
4 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Revealing the Neuroimaging Mechanism of Acupuncture for Poststroke Aphasia: A Systematic Review.Neural plasticity · 2022Pooled it
- The changed functional status of the brain was involved in patients with poststroke aphasia: Coordinate-based (activation likelihood estimation) meta-analysis.Brain and behavior · 2020Pooled it
- Enhanced left superior parietal activation during successful speech production in patients with left dorsal striatal damage and error-prone neurotypical participants.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Effects of non-invasive brain stimulation on spontaneous neural activity in post-stroke aphasia: a protocol for a coordinate-based meta-analysis of fALFF studies.Frontiers in neurologyArticle
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
background and purposeAlthough many functional magnetic resonance imaging (fMRI) studies have investigated the language architecture and neurobiological mechanism underlying poststroke aphasia (PSA), the pathophysiological mechanisms of PSA still remain poorly understood. In addition to a limited number of subjects (<20) tested with different methodologies and stimuli, inconsistent reports of the brain regions involved have been a major factor. Thus, we conducted a meta-analysis of 12 peer-reviewed studies of abnormal brain activation regions in PSA patients at rest using activation likelihood estimation (ALE).
resultsA meta-analysis was performed based on 24 experiments with 497 total participants in 12 studies to establish the ALE of regional activation in PSA. Through experiments with PSA patients and healthy controls, we found that hypoactivation in PSA converged on the left superior frontal gyrus and the left parietal postcentral gyrus, whereas there was hyperactivation in the right cerebellar anterior lobe, left fusiform gyrus, left superior parietal lobule, and right subgyral hippocampus.
conclusionOur study verified that dominant and nondominant language networks play roles in the recovery of language function.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.