ArticleCatheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions2021
Validation of novel 3-dimensional quantitative coronary angiography based software to calculate fractional flow reserve post stenting.
Article in Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 22 citations in OpenAlex.
- Diagnostic accuracy of angiography-based vessel fractional flow reserve after chronic coronary total occlusion recanalization.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2022Trial
- The impact of residual vessel fractional flow reserve on clinical outcomes: The FAST residual study.International journal of cardiology. Heart & vasculature · 2026Article
- Angiography-Derived Physiology for Coronary Artery Disease Assessment: Expert Opinion From a SCAI Roundtable.Journal of the Society for Cardiovascular Angiography & Interventions · 2026Review
- From Evidence to Practice: The Growing Role of Angiography-Derived Physiology.Journal of clinical medicine · 2025Review
- Angiographically-derived fractional flow reserve and optical coherence tomography findings after coronary stenting.International journal of cardiology. Heart & vasculature · 2025Article
- Association between post-PCI vessel fractional flow reserve (vFFR) and optical coherence tomography (OCT) findings: Results from the FAST OCT study.International journal of cardiology. Heart & vasculature · 2025Article
- Patient-specificFrontiers in cardiovascular medicine · 2024Review
- Study design and rationale of the angio-based final functional effect of PCI (AFFE PCI) study: a prospective multi-center study of post-PCI vFFR impact on clinical outcomes and residual angina.Cardiology journal · 2024Article
- Coronary Angiography Upgraded by Imaging Post-Processing: Present and Future Directions.Diagnostics (Basel, Switzerland) · 2023Review
- Current status and future perspectives of fractional flow reserve derived from invasive coronary angiography.Frontiers in cardiovascular medicine · 2023Review
- Angiography-Based Fractional Flow Reserve: State of the Art.Current cardiology reports · 2022Review
- Diagnostic Accuracy of Coronary Angiography-Based Vessel Fractional Flow Reserve (vFFR) Virtual Stenting.Journal of clinical medicine · 2022Article
- Validation of novel 3-dimensional quantitative coronary angiography based software to calculate fractional flow reserve post stenting.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2021Article
- Agreement Between Invasive Wire-Based and Angiography-Based Vessel Fractional Flow Reserve Assessment on Intermediate Coronary Stenoses.Frontiers in cardiovascular medicine · 2021Article
- Agreement of Angiography-Derived and Wire-Based Fractional Flow Reserves in Percutaneous Coronary Intervention.Frontiers in cardiovascular medicine · 2021Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo validate novel dedicated 3D-QCA based on the software to calculate post PCI vessel-FFR (vFFR) in a consecutive series of patients, to assess the diagnostic accuracy, and to assess inter-observer variability.
backgroundLow post percutaneous coronary intervention (PCI) fractional flow reserve (FFR) predicts future adverse cardiac events. However, FFR assessment requires the insertion of a pressure wire in combination with the use of a hyperemic agent.
methodsFAST POST study is an observational, retrospective, single-center cohort study. One hundred patients presenting with stable angina or non ST-elevation myocardial infarction, who underwent post PCI FFR assessment using a dedicated microcatheter were included. Two orthogonal angiographic projections were acquired to create a 3D reconstruction of the coronary artery using the CAAS workstation 8.0. vFFR was subsequently calculated using the aortic root pressure.
resultsMean age was 65±12 years and 70% were male. Mean microcatheter based FFR and vFFR were 0.91±0.07 and 0.91±0.06, respectively. A good linear correlation was found between FFR and vFFR (r = 0.88; p <.001). vFFR had a higher accuracy in the identification of patients with FFR values <0.90, AUC 0.98 (95% CI: 0.96-1.00) as compared with 3D-QCA AUC 0.62 (95% CI: 0.94-0.74). Assessment of vFFR had a low inter-observer variability (r = 0.95; p <.001).
conclusion3D-QCA derived post PCI vFFR correlates well with invasively measured microcatheter based FFR and has a high diagnostic accuracy to detect FFR <0.90 with low inter-observer variability.
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