Evidence map›Paper›PMID 33021859›Full record

ArticleOcular immunology and inflammation2022

Correlation between Subfoveal Choroidal Thickness and Anterior Segment Inflammation in Patients with Chronic Stage of Vogt-Koyanagi-Harada Disease.

Maria Soledad Ormaechea, Muhammad Hassan, Sarakshi Mahajan, Quan Dong Nguyen, Cristobal Couto, Ariel Schlaen

Open access · greenAbstract read
In one paragraph

Article in Ocular immunology and inflammation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Adalimumab treatment for chronic recurrent Vogt-Koyanagi-Harada disease with sunset glow fundus: A multicenter study.Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Maria Soledad OrmaecheaDepartment of Ophthalmology, Hospital Universitario Austral, Buenos Aires, Argentina.
Muhammad HassanDepartment of Ophthalmology, Byers Eye Institute, Stanford University, Palo Alto, California, USA.
Sarakshi MahajanDepartment of Ophthalmology, Byers Eye Institute, Stanford University, Palo Alto, California, USA.
Quan Dong NguyenDepartment of Ophthalmology, Byers Eye Institute, Stanford University, Palo Alto, California, USA.
Cristobal CoutoDepartment of Ophthalmology, Hospital Universitario Austral, Buenos Aires, Argentina.
Ariel SchlaenDepartment of Ophthalmology, Hospital Universitario Austral, Buenos Aires, Argentina.
Hospital Universitario Austral · ARStanford University · US

Funding

Stanford Vision Research CoreP30EY026877 · NEI · STANFORD UNIVERSITY · PI Jeffrey L Goldberg · 2017 to 2026
$8.0M
NEI NIH HHS P30 EY026877
6 · The paper itself

Abstract

purposeTo correlate changes in subfoveal choroidal thickness (SCT) with the degree of anterior inflammatory activity in chronic Vogt-Koyanagi-Harada (VKH) disease.

methodsAnterior segment inflammation was assessed using SUN anterior chamber cell grading criteria, and SCT was measured using EDI-OCT in patients with VKH at multiple visits. ANOVA was used to compare the mean SCT for each anterior chamber cell grade. Regression analysis was used to correlate the anterior segment cell grade and the SCT.

results14 patients were included in the study. A total of 432 data points consisting of SCT and anterior segment cell values were analyzed. ANOVA demonstrated significant difference between the mean SCT for different anterior chamber cell grades (

conclusionsChronic VKH is characterized by a dynamic change in SCT that correlates with anterior segment inflammatory activity.

Indexed as

Uveomeningoencephalitic SyndromeChoroidHumansInflammationOrgan SizeTomography, Optical Coherenceanterior segment inflammationEDI-OCTsubfoveal choroidal thicknessuveitisVogt Koyanagi Harada Disease

Identifiers

PMID33021859
PMCPMC10863988
OpenAlexW3092257793

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.