Evidence map›Paper›PMID 33021761›Full record

ArticleTurkish journal of medical sciences2021

Cerebral hemodynamic alterations in patients with Covid-19

Ali Rıza Sonkaya, Bilgin Öztrk, Ömer Karadaş

Abstract read
In one paragraph

Article in Turkish journal of medical sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Cardiac effects and comorbidities of neurological diseases.Turkish journal of medical sciences · 2024
    Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. How to monitor the brain in COVID-19 patients?Intensive & critical care nursing · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ali Rıza SonkayaDepartment of Neurology, University of Health Science, Gülhane School of Medicine, Ankara, TurkeyORCID 0000-0001-9218-4502
Bilgin ÖztrkDepartment of Neurology, University of Health Science, Gülhane School of Medicine, Ankara, TurkeyORCID 0000-0002-8899-9925
Ömer KaradaşDepartment of Neurology, University of Health Science, Gülhane School of Medicine, Ankara, TurkeyORCID 0000-0003-0457-3722

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background/aim: Coronavirus 2019 disease (Covid-19) was first seen in December 2019 and afterwards it became pandemic. Several systemic involvements have been reported in Covid-19 patients. In this study, it was aimed to investigate the cerebrovascular hemodynamics in patients with Covid-19. Materials and methods: The sample of this study included 20 patients hospitalized in our clinic diagnosed with Covid-19 via PCR modality and 20 healthy volunteers of similar age and sex. Bilateral middle cerebral arteries were investigated with transcranial Doppler ultrasonography. Basal cerebral blood flow velocities and vasomotor reactivity rates were determined and statistically compared. Results: When patient and control groups were compared, the mean blood flow velocity was found to be higher in Covid-19 patients than in the healthy volunteers and it was statistically significant (P = 0.00). The mean vasomotor reactivity rates values were found to be lower in the Covid-19 group than the healthy group and was also statistically significant (P = 0.00). Conclusion: An increase in basal cerebral blood velocity and a decrease in vasomotor reactivity rates in patients with Covid-19 can be considered as an indicator of dysfunction of cerebral hemodynamics in the central nervous system and this can be evaluated as a result of endothelial dysfunction.

Indexed as

AdultAgedAged, 80 and overBlood Flow VelocityCase-Control StudiesCerebrovascular CirculationCOVID-19FemaleHemodynamicsHumansMaleMiddle AgedMiddle Cerebral ArterySARS-CoV-2Ultrasonography, Doppler, TranscranialVasomotor Systemblood flow velocityCovid-19SARS-Cov-2vasomotor reactivity

Identifiers

PMID33021761
PMCPMC8203147

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.