Evidence map›Paper›PMID 33021367›Full record

ArticleAnnals of surgery2020

Yield of Screening for COVID-19 in Asymptomatic Patients Before Elective or Emergency Surgery Using Chest CT and RT-PCR (SCOUT): Multicenter Study.

Carl A J Puylaert, Jochem C G Scheijmans, Alexander B J Borgstein, Caroline S Andeweg, Annemarieke Bartels-Rutten, Geerard L Beets, Mark I van Berge Henegouwen, Sicco J Braak, Roy Couvreur, Freek Daams and 45 more

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in Annals of surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 5 pooled it
3.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 5 syntheses or guidelines pooled it, 52 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Thoracic imaging tests for the diagnosis of COVID-19.The Cochrane database of systematic reviews · 2022
    Pooled it
  4. Asymptomatic SARS-CoV-2 infection: A systematic review and meta-analysis.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Pooled it
  5. Pooled it
  6. Article
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  9. Article
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  12. Observational
  13. Article
  14. Safe provision of elective endocrine surgery operations amid the COVID-19 crisis.Annals of the Royal College of Surgeons of England · 2022
    Article
  15. Observational
  16. Article
  17. Article
  18. What Is COVID 19 Teaching Us about Pulmonary Ultrasound?Diagnostics (Basel, Switzerland) · 2022
    Review
  19. Article
  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

55 authors at 15 institutions in 1 country.

Carl A J PuylaertDepartment of Radiology and Nuclear Medicine, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
Jochem C G ScheijmansDepartment of Surgery, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
Alexander B J BorgsteinDepartment of Surgery, Cancer Center Amsterdam, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
Caroline S AndewegDepartment of Surgery, St Jansdal Hospital, Harderwijk, the Netherlands.
Annemarieke Bartels-RuttenDepartment of Radiology, Netherlands Cancer Institute, Amsterdam, the Netherlands.
Geerard L BeetsDepartment of Surgical Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands.
Mark I van Berge HenegouwenDepartment of Surgery, Cancer Center Amsterdam, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
Sicco J BraakDepartment of Radiology, Hospital Group Twente, Almelo, the Netherlands.
Roy CouvreurDepartment of Surgery, Haaglanden Medical Center, Den Haag, the Netherlands.
Freek DaamsDepartment of Surgery, Cancer Center Amsterdam UMC, VU University Amsterdam, Amsterdam, the Netherlands.
Hendrik W van EsDepartment of Radiology, Sint Antonius Hospital, Nieuwegein, the Netherlands.
Lotte C FrankenDepartment of Surgery, Flevo Hospital, Almere, the Netherlands.
Brechtje A GrotenhuisDepartment of Surgical Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands.
Eduard R HendriksDepartment of Surgery, Tergooi Hospitals, Hilversum, the Netherlands.
Ignace H J T de HinghDepartment of Surgery, Catharina Hospital, Eindhoven, the Netherlands.
Fieke HoeijmakersDepartment of Surgery, Dijklander Hospital, Hoorn, the Netherlands.
Joris T Ten HolderDepartment of Pulmonary Medicine, Haaglanden Medical Center, Den Haag, the Netherlands.
Peter M HuismanDepartment of Radiology, Tergooi Hospitals, Hilversum, the Netherlands.
Geert KazemierDepartment of Surgery, Cancer Center Amsterdam UMC, VU University Amsterdam, Amsterdam, the Netherlands.
Floortje van KesterenDepartment of Radiology, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
Jurre van KesterenDepartment of Surgery, Dijklander Hospital, Hoorn, the Netherlands.
Kammy KeywaniDepartment of Surgery, Cancer Center Amsterdam, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
Sara Z KuiperDepartment of Surgery, Maastricht UMC+, Maastricht, the Netherlands.
Maurits D J LangeDepartment of Surgical Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands.
Mark E LobattoDepartment of Radiology, Spaarne Gasthuis, Haarlem and Hoofddorp, the Netherlands.
Arthur W F du MéeDepartment of Radiology, Amphia Hospital, Breda, the Netherlands.
Martijn PoezeDepartment of Surgery, Maastricht UMC+, Maastricht, the Netherlands.
Elise M van PraagDepartment of Surgery, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
Jorit van RossenDepartment of Radiology, Hospital Group Twente, Almelo, the Netherlands.
Hjalmar C van SantvoortDepartment of Surgery, Sint Antonius Hospital, Nieuwegein, the Netherlands.
Wouter J A SedeeDepartment of Emergency Medicine, St Jansdal Hospital, Harderwijk, the Netherlands.
Leonard W F SeelenDepartment of Surgery, Sint Antonius Hospital, Nieuwegein, the Netherlands.
Sarah SharabianyDepartment of Surgery, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
Nico L SosefDepartment of Surgery, Spaarne Gasthuis, Haarlem and Hoofddorp, the Netherlands.
Marian J R QuanjelDepartment of Pulmonary Medicine, Sint Antonius Hospital, Nieuwegein, the Netherlands.
Jeroen VeltmanDepartment of Radiology, Hospital Group Twente, Almelo, the Netherlands.
Tim VerhagenDepartment of Surgery, Hospital Group Twente, Almelo, the Netherlands.
Vincent C J van de VlasakkerDepartment of Surgery, Catharina Hospital, Eindhoven, the Netherlands.
Pepijn D WeederDepartment of Surgery, Spaarne Gasthuis, Haarlem and Hoofddorp, the Netherlands.
Jochem R van WervenDepartment of Radiology, Amphia Hospital, Breda, the Netherlands.
Nina J WesdorpDepartment of Surgery, Cancer Center Amsterdam UMC, VU University Amsterdam, Amsterdam, the Netherlands.
Susan van DierenDepartment of Surgery, Cancer Center Amsterdam, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
Alvin X HanLaboratory of Applied Evolutionary Biology, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
Colin A RussellLaboratory of Applied Evolutionary Biology, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
Menno D de JongDepartment of Medical Microbiology and Infection Prevention, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
Patrick M M BossuytDepartment of Clinical Epidemiology, Biostatistics and Bioinformatics, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
Jet M E Quarles van UffordDepartment of Radiology, Haaglanden Medical Center, Den Haag, the Netherlands.
Mathias W ProkopDepartment of Radiology, Radboud UMC, Nijmegen, the Netherlands.
Suzanne S GisbertzDepartment of Surgery, Cancer Center Amsterdam, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
Jan M PrinsDepartment of Internal Medicine, Division of Infectious Diseases, Amsterdam Institute for Infection and Immunity (AI&II), Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
Marc G BesselinkDepartment of Surgery, Cancer Center Amsterdam, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
Marja A BoermeesterDepartment of Surgery, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
Hester A GietemaDepartment of Radiology, Maastricht UMC+, Maastricht, the Netherlands.
Jaap StokerDepartment of Radiology and Nuclear Medicine, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
SCOUT study group
Amsterdam University Medical Centers · NLUniversity of Amsterdam · NLThe Netherlands Cancer Institute · NLAmsterdam Neuroscience · NLMaastricht University Medical Centre · NLMedisch Centrum Haaglanden · NLRijnstate Hospital · NLSpaarne Gasthuis · NLTergooi · NLZiekenhuis Groep Twente · NLAmsterdam UMC Location VUmc · NLOncode Institute · NLRadboud University Nijmegen · NLReinier de Graaf Hospital · NLSt. Antonius Ziekenhuis · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine the yield of preoperative screening for COVID-19 with chest CT and RT-PCR in patients without COVID-19 symptoms. SUMMARY OF BACKGROUND DATA: Many centers are currently screening surgical patients for COVID-19 using either chest CT, RT-PCR or both, due to the risk for worsened surgical outcomes and nosocomial spread. The optimal design and yield of such a strategy are currently unknown.

methodsThis multicenter study included consecutive adult patients without COVID-19 symptoms who underwent preoperative screening using chest CT and RT-PCR before elective or emergency surgery under general anesthesia.

resultsA total of 2093 patients without COVID-19 symptoms were included in 14 participating centers; 1224 were screened by CT and RT-PCR and 869 by chest CT only. The positive yield of screening using a combination of chest CT and RT-PCR was 1.5% [95% confidence interval (CI): 0.8-2.1]. Individual yields were 0.7% (95% CI: 0.2-1.1) for chest CT and 1.1% (95% CI: 0.6-1.7) for RT-PCR; the incremental yield of chest CT was 0.4%. In relation to COVID-19 community prevalence, up to ∼6% positive RT-PCR was found for a daily hospital admission rate >1.5 per 100,000 inhabitants, and around 1.0% for lower prevalence.

conclusionsOne in every 100 patients without COVID-19 symptoms tested positive for SARS-CoV-2 with RT-PCR; this yield increased in conjunction with community prevalence. The added value of chest CT was limited. Preoperative screening allowed us to take adequate precautions for SARS-CoV-2 positive patients in a surgical population, whereas negative patients needed only routine procedures.

Indexed as

Asymptomatic InfectionsEmergency TreatmentReverse Transcriptase Polymerase Chain ReactionSARS-CoV-2Surgical Procedures, OperativeTomography, X-Ray ComputedCOVID-19Elective Surgical ProceduresHumansMass ScreeningPreoperative CareRetrospective StudiesThorax

Identifiers

PMID33021367
PMCPMC7668335
OpenAlexW3045408250

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.