Evidence map›Paper›PMID 33021196›Full record

ArticleThe American journal of tropical medicine and hygiene2020

Comparison of Smartphone Photography, Single-Lens Reflex Photography, and Field-Grading for Trachoma.

John M Nesemann, Michael I Seider, Blake M Snyder, Robi N Maamari, Daniel A Fletcher, Berhan A Haile, Zerihun Tadesse, Nicole E Varnado, Sun Y Cotter, Elizabeth Kelly Callahan and 4 more

Open access · bronzeAbstract readComparative Study
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 20 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Discrepancy Between Active Trachoma and Tests of Chlamydial Infection in Alto Amazonas, Peru.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Photographic grading for trachoma diagnosis within trachoma impact surveys in Amhara region, Ethiopia.Transactions of the Royal Society of Tropical Medicine and Hygiene · 2023
    Article
  10. Detection of trachoma using machine learning approaches.PLoS neglected tropical diseases · 2022
    Article
  11. Trachoma.Nature reviews. Disease primers · 2022
    Review
  12. Observational
  13. Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 2 countries.

John M Nesemann1Francis I Proctor Foundation, University of California, San Francisco, San Francisco, California.
Michael I Seider1Francis I Proctor Foundation, University of California, San Francisco, San Francisco, California.
Blake M Snyder1Francis I Proctor Foundation, University of California, San Francisco, San Francisco, California.
Robi N Maamari1Francis I Proctor Foundation, University of California, San Francisco, San Francisco, California.
Daniel A Fletcher4Department of Bioengineering, University of California, Berkeley, Berkeley, California.
Berhan A Haile5The Carter Center Ethiopia, Addis Ababa, Ethiopia.
Zerihun Tadesse5The Carter Center Ethiopia, Addis Ababa, Ethiopia.
Nicole E Varnado1Francis I Proctor Foundation, University of California, San Francisco, San Francisco, California.
Sun Y Cotter1Francis I Proctor Foundation, University of California, San Francisco, San Francisco, California.
Elizabeth Kelly Callahan6The Carter Center, Atlanta, Georgia.
Paul M Emerson6The Carter Center, Atlanta, Georgia.
Todd P Margolis7Department of Ophthalmology and Visual Sciences, Washington University School of Medicine in St. Louis, St. Louis, Missouri.
Thomas M Lietman1Francis I Proctor Foundation, University of California, San Francisco, San Francisco, California.
Jeremy D Keenan1Francis I Proctor Foundation, University of California, San Francisco, San Francisco, California.
University of California, San Francisco · USCarter Center · USSan Francisco Foundation · USThe Carter Center · ETUniversity of California, Berkeley · USUniversity of California, Los Angeles · US

Funding

University of California Launching Future Leaders in Global Health Research Training ProgramD43TW009343 · FIC · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CRAIG R COHEN, Sung-Jae Lee · 2017 to 2026
$14.7M
Village Integrated Eye Workers TrialU10EY022880 · NEI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LIETMAN, THOMAS M · 2013 to 2017
$2.3M
FIC NIH HHS D43 TW009343NEI NIH HHS U10 EY022880
6 · The paper itself

Abstract

Conjunctival examination for trachomatous inflammation-follicular (TF) guides public health decisions for trachoma. Smartphone cameras may allow remote conjunctival grading, but previous studies have found low sensitivity. A random sample of 412 children aged 1-9 years received an in-person conjunctival examination and then had conjunctival photographs taken with 1) a single-lens reflex (SLR) camera and 2) a smartphone coupled to a 3D-printed magnifying attachment. Three masked graders assessed the conjunctival photographs for TF. Latent class analysis was used to determine the sensitivity and specificity of each grading method for TF. Single-lens reflex photo-grading was 95.0% sensitive and 93.6% specific, and smartphone photo-grading was 84.1% sensitive and 97.6% specific. The sensitivity of the smartphone-CellScope device was considerably higher than that of a previous study using the native smartphone camera, without attachment. Magnification of smartphone images with a simple attachment improved the grading sensitivity while maintaining high specificity in a region with hyperendemic trachoma.

Indexed as

SmartphoneChildChild, PreschoolFemaleHumansInfantMalePhotographySensitivity and SpecificityTrachoma

Identifiers

PMID33021196
PMCPMC7695070
OpenAlexW3090423915

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.