ArticleNature communications2020
Fetal whole heart blood flow imaging using 4D cine MRI.
Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 29 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 53 citations in OpenAlex.
- Motion Mitigation Techniques for Abdominal and Cardiac MR Imaging.Journal of magnetic resonance imaging : JMRI · 2026Review
- Following the flow: in vivo imaging of fetal foramen ovale physiology using four-dimensional flow magnetic resonance imaging with doppler ultrasound gating.Radiology case reports · 2026Article
- Toward noninvasive optoacoustic imaging of whole-heart dynamics in mice.Light, science & applications · 2025Article
- The role of magnetic resonance imaging in fetal congenital heart disease.Pediatric radiology · 2025Review
- Characterizing fetoplacental response to acute maternal hyperoxygenation in suspected coarctation of aorta using fetal cardiac MRI.Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2025Article
- Fetal Cardiovascular Magnetic Resonance: History, Current Status, and Future Directions.Journal of magnetic resonance imaging : JMRI · 2025Review
- Third trimester fetal 4D flow MRI with motion correction.Magnetic resonance in medicine · 2025Article
- Reliability of 4D Flow MRI for Investigation of Fetal Cardiovascular Hemodynamics in the Third Trimester.Radiology. Cardiothoracic imaging · 2024Article
- The onset of coarctation of the aorta before birth: Mechanistic insights from fetal arch anatomy and haemodynamics.Computers in biology and medicine · 2024Article
- The New Frontiers of Fetal Imaging: MRI Insights into Cardiovascular and Thoracic Structures.Journal of clinical medicine · 2024Review
- Total and Regional Brain Volumes in Fetuses With Congenital Heart Disease.Journal of magnetic resonance imaging : JMRI · 2024Article
- Advances in Fetal Cardiac Imaging and Intervention.CJC pediatric and congenital heart disease · 2024Review
- Fetal and neonatal echocardiographic analysis of biomechanical alterations for the systemic right ventricle heart.PloS one · 2024Article
- Utility of Fetal Cardiac Resonance Imaging in Prenatal Clinical Practice: Current State of the Art.Diagnostics (Basel, Switzerland) · 2023Review
- Retrospective motion correction in foetal MRI for clinical applications: existing methods, applications and integration into clinical practice.The British journal of radiology · 2023Review
- Fetal cardiovascular blood flow MRI: techniques and applications.The British journal of radiology · 2023Review
- Learning the Hidden Signature of Fetal Arch Anatomy: a Three-Dimensional Shape Analysis in Suspected Coarctation of the Aorta.Journal of cardiovascular translational research · 2023Article
- Fetal MRI at 3 T: Principles to Optimize Success.Radiographics : a review publication of the Radiological Society of North America, Inc · 2023Article
- The current state and potential innovation of fetal cardiac MRI.Frontiers in pediatrics · 2023Review
- Advanced imaging of fetal cardiac function.Frontiers in cardiovascular medicine · 2023Review
Corrections and comments
- Erratum issued
Authors and funding
15 authors at 1 institution in 1 country.
Funding
Abstract
Prenatal detection of congenital heart disease facilitates the opportunity for potentially life-saving care immediately after the baby is born. Echocardiography is routinely used for screening of morphological malformations, but functional measurements of blood flow are scarcely used in fetal echocardiography due to technical assumptions and issues of reliability. Magnetic resonance imaging (MRI) is readily used for quantification of abnormal blood flow in adult hearts, however, existing in utero approaches are compromised by spontaneous fetal motion. Here, we present and validate a novel method of MRI velocity-encoding combined with a motion-robust reconstruction framework for four-dimensional visualization and quantification of blood flow in the human fetal heart and major vessels. We demonstrate simultaneous 4D visualization of the anatomy and circulation, which we use to quantify flow rates through various major vessels. The framework introduced here could enable new clinical opportunities for assessment of the fetal cardiovascular system in both health and disease.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.