ArticleInternational journal of environmental research and public health2020
Association of Periodontitis with Atherosclerotic Cardiovascular Diseases: A Nationwide Population-based Retrospective Matched Cohort Study.
Article in International journal of environmental research and public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.
- Association between Dental and Cardiovascular Diseases: A Systematic Review.Reviews in cardiovascular medicine · 2023Pooled it
- Dental Anxiety as a Potential Bottleneck in Oral-Systemic Health Pathways: A Conceptual Mapping Review of Review Articles.Dentistry journal · 2026Review
- Tooth Loss as a Predictor of Coronary Artery Disease Severity in Patients with Acute Myocardial Infarction: A Prospective Cross-Sectional Study.Journal of clinical medicine · 2026Article
- Effects of periodontitis on micro and macro vascular complications of diabetes: A systematic review.Journal of advanced periodontology & implant dentistry · 2026Article
- A Two-Way Communication Between Apical Periodontitis and Various Systemic Disorders: A Narrative Review.Cureus · 2025Review
- Severe Tooth Loss and Cardiovascular Disease Among Older Adults in Hawai'i: A Cross-Sectional Study of Behavioral Risk Factor Surveillance System Data from 2012 to 2020.Hawai'i journal of health & social welfare · 2025Article
- Apical periodontitis and its effects on renal tissue in rats.Revista peruana de medicina experimental y salud publica · 2025Article
- Young hearts at risk: Unveiling novel factors in myocardial infarction susceptibility and prevention.Journal of family medicine and primary care · 2024Review
- Association between Endodontic Infection, Its Treatment and Systemic Health: A Narrative Review.Medicina (Kaunas, Lithuania) · 2022Review
- Is There a Link between COVID-19 Infection, Periodontal Disease and Acute Myocardial Infarction?Life (Basel, Switzerland) · 2021Review
- Periodontal Disease Is Associated with Increased Vulnerability of Coronary Atheromatous Plaques in Patients Undergoing Coronary Computed Tomography Angiography-Results from the Atherodent Study.Journal of clinical medicine · 2021Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We investigated the association between periodontitis and atherosclerotic cardiovascular disease (ACVD) development using the National Health Insurance Service-National Sample Cohort 2.0 (NHIS-NSC2) database, which contains data for approximately 1 million nationally representative random participants. We selected 52,425 participants aged 20+ years and diagnosed with periodontitis from January to December 2003 and used propensity score matching to select an equivalent number of participants who were never diagnosed with periodontitis in the period covered by the NHIS-NSC2 database (2002-2015). The propensity scores were based on sex, age group, type of national health insurance, household income, diabetes status, and hypertension status and were used for 1:1 matching of individuals with similar propensities. A total of 104,850 participants were selected for the study. A multivariable Cox proportional hazard regression model was used to investigate the risk of ACVD development due to periodontitis from 2003 to 2015 after adjusting for sex, age, type of national health insurance, household income, hypertension status, and diabetes status. Participants with periodontitis had a higher risk of ACVD (adjusted hazard ratio: 1.09, 95% confidence interval: 1.05-1.13) than those without periodontitis. Thus, periodontitis can increase the risk of ACVD, and prevention of periodontitis may help reduce the risk of cardiovascular disease.
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Registered trials
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