Evidence map›Paper›PMID 33020222›Full record

ArticleJournal of bacteriology2020

Degradation of Lon in Caulobacter crescentus.

Benjamin B Barros, Samar A Mahmoud, Peter Chien, Rilee D Zeinert

Open access · greenAbstract read
In one paragraph

Article in Journal of bacteriology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Proteomic survey of the DNA damage response inJournal of bacteriology · 2023
    Article
  4. Proteomic survey of the DNA damage response inbioRxiv : the preprint server for biology · 2023
    Article
  5. Review
  6. Article
  7. Article
  8. The Protein Quality Control Network inFrontiers in molecular biosciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Benjamin B BarrosDepartment of Biochemistry and Molecular Biology, University of Massachusetts Amherst, Amherst, Massachusetts, USA.
Samar A MahmoudMolecular and Cellular Biology Program, University of Massachusetts Amherst, Amherst, Massachusetts, USA.
Peter ChienDepartment of Biochemistry and Molecular Biology, University of Massachusetts Amherst, Amherst, Massachusetts, USA pchien@umass.edu rileezeinert@gmail.com.ORCID 0000-0001-6733-1478
Rilee D ZeinertDepartment of Biochemistry and Molecular Biology, University of Massachusetts Amherst, Amherst, Massachusetts, USA pchien@umass.edu rileezeinert@gmail.com.
University of Massachusetts Amherst · US

Funding

CHEMISTRY-BIOLOGY INTERFACE PREDOCTORAL TRAINING GRANTST32GM008515 · NIGMS · UNIVERSITY OF MASSACHUSETTS AMHERST · PI THOMPSON, LYNMARIE K. · 1995 to 2020
$4.3M
Regulated Proteolysisin Bacteria Development and Stress ResponseR35GM130320 · NIGMS · UNIVERSITY OF MASSACHUSETTS AMHERST · PI Peter Chien · 2019 to 2026
$3.4M
Howard Hughes Medical InstituteNIGMS NIH HHS R35 GM130320NIGMS NIH HHS T32 GM008515
6 · The paper itself

Abstract

Protein degradation is an essential process in all organisms. This process is irreversible and energetically costly; therefore, protein destruction must be tightly controlled. While environmental stresses often lead to upregulation of proteases at the transcriptional level, little is known about posttranslational control of these critical machines. In this study, we show that in

Indexed as

Amino Acid SequenceBlotting, WesternCaulobacter crescentusEndopeptidase ClpFlow CytometryMicroscopy, Phase-ContrastPlasmidsProtease LaProteolysisEndopeptidase ClpProtease LaAAA+Caulobacter crescentusdegradationLonprotease

Identifiers

PMID33020222
PMCPMC7723953
OpenAlexW3091332561

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.