Evidence map›Paper›PMID 33020211›Full record

ArticleInfection and immunity2020

Secretion of c-di-AMP by Listeria monocytogenes Leads to a STING-Dependent Antibacterial Response during Enterocolitis.

Alexander Louie, Varaang Bhandula, Daniel A Portnoy

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Infection and immunity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. The STING signaling pathways and bacterial infection.Apoptosis : an international journal on programmed cell death · 2025
    Review
  3. Article
  4. Genomic Distribution of Pro-VirulentInternational journal of molecular sciences · 2023
    Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Innate immune sensing by epithelial barriers.Current opinion in immunology · 2021
    Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Alexander LouieDepartment of Molecular and Cell Biology, University of California, Berkeley, Berkeley, California, USA.
Varaang BhandulaDepartment of Molecular and Cell Biology, University of California, Berkeley, Berkeley, California, USA.
Daniel A PortnoyDepartment of Molecular and Cell Biology, University of California, Berkeley, Berkeley, California, USA portnoy@berkeley.edu.ORCID 0000-0003-1218-2799
University of California, Berkeley · US

Funding

The role of Listeria cyclic-di-AMP during infection and immunityP01AI063302 · NIAID · UNIVERSITY OF CALIFORNIA BERKELEY · PI STANLEY, SARAH A · 2004 to 2025
$45.5M
Listeria Hemolysis and Escape From a VacuoleR01AI027655 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI DANIEL A PORTNOY · 1993 to 2026
$10.1M
Immunology & Pathogenesis Program Training GrantT32AI100829 · NIAID · UNIVERSITY OF CALIFORNIA BERKELEY · PI Gregory M Barton, ELLEN A ROBEY · 2012 to 2026
$4.7M
NIAID NIH HHS P01 AI063302NIAID NIH HHS R01 AI027655NIAID NIH HHS T32 AI100829
6 · The paper itself

Abstract

Stimulator of interferon genes (STING) acts as a cytoplasmic signaling hub of innate immunity that is activated by host-derived or bacterially derived cyclic dinucleotides.

Indexed as

AnimalsDinucleoside PhosphatesEnterocolitisFlow CytometryImmunity, InnateInterferon Type IListeria monocytogenesListeriosisMembrane ProteinsMiceMice, Inbred C57BLMice, KnockoutMonocytesSignal TransductionSTING Proteincyclic diadenosine phosphateDinucleoside PhosphatesInterferon Type IMembrane ProteinsSting1 protein, mouseSTING Proteingastrointestinal infectioninnate immunityListeria monocytogenesmonocytespathogenesis

Identifiers

PMID33020211
PMCPMC7671888
OpenAlexW3089426223

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.