Evidence map›Paper›PMID 33020192›Full record

ArticleG3 (Bethesda, Md.)2020

Enhanced Efficiency of flySAM by Optimization of sgRNA Parameters in

Decai Mao, Yu Jia, Ping Peng, Da Shen, Xingjie Ren, Ruibao Zhu, Yuhao Qiu, Yuting Han, Jinchao Yu, Qinyun Che and 7 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in G3 (Bethesda, Md.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 4 institutions in 1 country.

Decai MaoGene Regulatory Lab, School of Medicine, Tsinghua University, Beijing 100084, China.
Yu JiaGene Regulatory Lab, School of Medicine, Tsinghua University, Beijing 100084, China.
Ping PengGene Regulatory Lab, School of Medicine, Tsinghua University, Beijing 100084, China.
Da ShenGene Regulatory Lab, School of Medicine, Tsinghua University, Beijing 100084, China.
Xingjie RenGene Regulatory Lab, School of Medicine, Tsinghua University, Beijing 100084, China.
Ruibao ZhuGene Regulatory Lab, School of Medicine, Tsinghua University, Beijing 100084, China.
Yuhao QiuGene Regulatory Lab, School of Medicine, Tsinghua University, Beijing 100084, China.
Yuting HanGene Regulatory Lab, School of Medicine, Tsinghua University, Beijing 100084, China.
Jinchao YuGene Regulatory Lab, School of Medicine, Tsinghua University, Beijing 100084, China.
Qinyun CheGene Regulatory Lab, School of Medicine, Tsinghua University, Beijing 100084, China.
Yutong LiGene Regulatory Lab, School of Medicine, Tsinghua University, Beijing 100084, China.
Xinyi LuGene Regulatory Lab, School of Medicine, Tsinghua University, Beijing 100084, China.
Lu-Ping LiuGene Regulatory Lab, School of Medicine, Tsinghua University, Beijing 100084, China.
Zhao WangSchool of Pharmaceutical Sciences, Tsinghua University, 100084 Beijing, China.
Qingfei LiuSchool of Pharmaceutical Sciences, Tsinghua University, 100084 Beijing, China.
Jin SunGene Regulatory Lab, School of Medicine, Tsinghua University, Beijing 100084, China sunjin2017@mail.tsinghua.edu.cn nijq@mail.tsinghua.edu.cn.ORCID 0000-0003-2684-0078
Jian-Quan NiGene Regulatory Lab, School of Medicine, Tsinghua University, Beijing 100084, China sunjin2017@mail.tsinghua.edu.cn nijq@mail.tsinghua.edu.cn.
Tsinghua University · CNCenter for Life Sciences · CNShandong First Medical University · CNTongji University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The flySAM/CRISPRa system has recently emerged as a powerful tool for gain-of-function studies in

Indexed as

DrosophilaDrosophila melanogasterAnimalsBase CompositionCRISPR-Cas SystemsPromoter Regions, GeneticRNA, Guide, CRISPR-Cas SystemsTranscription Initiation SiteRNA, Guide, CRISPR-Cas SystemsDNA strandflySAMGC contentposition effectsgRNA

Identifiers

PMID33020192
PMCPMC7718753
OpenAlexW3089549916

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.