Evidence map›Paper›PMID 33020160›Full record

ArticleAntimicrobial agents and chemotherapy2020

Olorofim Susceptibility Testing of 1,423 Danish Mold Isolates Obtained in 2018-2019 Confirms Uniform and Broad-Spectrum Activity.

Karen Marie Thyssen Astvad, Karin Meinike Jørgensen, Rasmus Krøger Hare, Raluca Datcu, Maiken Cavling Arendrup

Open access · greenAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Genomic Insights ofOpen forum infectious diseases · 2026
    Review
  6. Article
  7. Olorofim activity against multidrug-resistantAntimicrobial agents and chemotherapy · 2025
    Article
  8. Successful use of olorofim for the treatment ofAntimicrobial agents and chemotherapy · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Antimicrobial agents and chemotherapy · 2025
    Article
  13. Article
  14. Article
  15. Review
  16. Refractory versus resistant invasive aspergillosis.The Journal of antimicrobial chemotherapy · 2025
    Review
  17. Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Karen Marie Thyssen AstvadUnit of Mycology, Statens Serum Institut, Copenhagen, Denmark.ORCID 0000-0002-4651-2904
Karin Meinike JørgensenUnit of Mycology, Statens Serum Institut, Copenhagen, Denmark.
Rasmus Krøger HareUnit of Mycology, Statens Serum Institut, Copenhagen, Denmark.ORCID 0000-0002-9796-023X
Raluca DatcuUnit of Mycology, Statens Serum Institut, Copenhagen, Denmark.
Maiken Cavling ArendrupUnit of Mycology, Statens Serum Institut, Copenhagen, Denmark maca@ssi.dk.ORCID 0000-0002-4747-0144
Statens Serum Institut · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Olorofim is a novel antifungal drug in phase 2 trials. It has shown promising

Indexed as

PyrimidinesTriazolesAcetamidesAntifungal AgentsArthrodermataceaeAspergillus fumigatusDenmarkDrug Resistance, FungalMicrobial Sensitivity TestsPiperazinesPyrrolesAcetamidesAntifungal AgentsolorofimPiperazinesPyrimidinesPyrrolesTriazolesantifungal susceptibilityAspergillusazole resistanceCyp51ADHODHEUCASTF901318olorofimpyrEScedosporium

Identifiers

PMID33020160
PMCPMC7927864
OpenAlexW3089391639

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.