Evidence map›Paper›PMID 33020106›Full record

ArticleBMJ open2020

Age differences in clinical features and outcomes in patients with COVID-19, Jiangsu, China: a retrospective, multicentre cohort study.

Huanyuan Luo, Songqiao Liu, Yuancheng Wang, Penelope A Phillips-Howard, Shenghong Ju, Yi Yang, Duolao Wang

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in BMJ open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 3 pooled it
1.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 3 syntheses or guidelines pooled it, 52 citations in OpenAlex.

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  7. Immunity and Coagulation in COVID-19.International journal of molecular sciences · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Huanyuan Luo *Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
Songqiao Liu *Jiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China.
Yuancheng WangDepartment of Radiology, Southeast University Zhongda Hospital, Nanjing, China.
Penelope A Phillips-HowardDepartment of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
Shenghong JuDepartment of Radiology, Southeast University Zhongda Hospital, Nanjing, China.ORCID 0000-0002-2497-4286
Yi YangJiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China yiyiyang2004@163.com Duolao.Wang@lstmed.ac.uk.
Duolao WangDepartment of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, United Kingdom yiyiyang2004@163.com Duolao.Wang@lstmed.ac.uk.ORCID 0000-0003-2788-2464
Zhongda Hospital Southeast University · CNLiverpool School of Tropical Medicine · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo determine the age-specific clinical presentations and incidence of adverse outcomes among patients with COVID-19 in Jiangsu, China. DESIGN AND

settingRetrospective, multicentre cohort study performed at 24 hospitals in Jiangsu, China.

participants625 patients with COVID-19 enrolled between 10 January and 15 March 2020.

resultsOf the 625 patients (median age, 46 years; 329 (52.6%) men), 37 (5.9%) were children (18 years or younger), 261 (41.8%) young adults (19-44 years), 248 (39.7%) middle-aged adults (45-64 years) and 79 (12.6%) elderly adults (65 years or older). The incidence of hypertension, coronary heart disease, chronic obstructive pulmonary disease and diabetes comorbidities increased with age (trend test, p<0.0001, p=0.0003, p<0.0001 and p<0.0001, respectively). Fever, cough and shortness of breath occurred more commonly among older patients, especially the elderly, compared with children (χ

conclusionsElderly (≥65 years) patients with COVID-19 had the highest risk of severe or critical illness, intensive care use, respiratory failure and the longest hospital stay, which may be due partly to their having a higher incidence of comorbidities and poor immune responses to COVID-19.

Indexed as

Age FactorsCoronavirus InfectionsCritical CarePandemicsPneumonia, ViralSymptom AssessmentAdolescentAgedBetacoronavirusChinaCohort StudiesComorbidityCOVID-19Critical IllnessFemaleHumansepidemiologyinfectious diseasespublic health

Identifiers

PMID33020106
PMCPMC7536631
OpenAlexW3090106850

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.