Evidence map›Paper›PMID 33020099›Full record

Observational studyBMJ open2020

Impact of COPD case finding on clinical care: a prospective analysis of the TargetCOPD trial.

Shamil Haroon, Peymane Adab, Andrew P Dickens, Alice J Sitch, Kiran Rai, Alexandra Enocson, David A Fitzmaurice, Rachel E Jordan

Abstract readObservational Study
In one paragraph

Observational study in BMJ open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shamil HaroonInstitute of Applied Health Research, University of Birmingham, Birmingham, UK s.haroon@bham.ac.uk.ORCID 0000-0002-0096-1413
Peymane AdabInstitute of Applied Health Research, University of Birmingham, Birmingham, UK.ORCID 0000-0001-9087-3945
Andrew P DickensInstitute of Applied Health Research, University of Birmingham, Birmingham, UK.ORCID 0000-0002-7591-8129
Alice J SitchInstitute of Applied Health Research, University of Birmingham, Birmingham, UK.ORCID 0000-0001-7727-4497
Kiran RaiInstitute of Applied Health Research, University of Birmingham, Birmingham, UK.ORCID 0000-0002-3250-0275
Alexandra EnocsonInstitute of Applied Health Research, University of Birmingham, Birmingham, UK.
David A FitzmauriceWarwick Medical School - Health Sciences, University of Warwick, Coventry, UK.
Rachel E JordanInstitute of Applied Health Research, University of Birmingham, Birmingham, UK.

Funding

Department of Health RP-PG-0109-10061
6 · The paper itself

Abstract

objectivesTo investigate the impact of chronic obstructive pulmonary disease (COPD) case finding on clinical care.

designWe conducted a prospective observational analysis of data from a pragmatic cluster randomised controlled trial in primary care in the West Midlands, UK (TargetCOPD). This compared alternative methods of COPD case finding against usual care. Data were extracted from electronic healthcare records and self-reported questionnaires for a subset of patients with newly diagnosed COPD.

setting50 general practices that participated in the TargetCOPD trial.

participantsPatients aged 40-79 years newly identified with COPD by targeted case finding or by usual care, from 10 August 2012 to 22 June 2014. PRIMARY AND SECONDARY OUTCOME MEASURES: The primary outcome was addition to a COPD register by the end of the trial. The secondary outcome was a clinical care score, derived from the sum of clinical assessments and relevant interventions. Associations between participant characteristics and the primary and secondary outcomes were assessed using multilevel regression.

results857 patients identified with COPD by case finding and 764 by usual care were included. Only 21.2% of case-found patients had been added to a COPD register, compared with 92.7% of those diagnosed by usual care. The odds of being added were greater in smokers (adjusted OR 8.68, 95% CI 2.53 to 29.8), and in those with lower percentage of predicted forced expiratory volume in 1 s (adjusted OR 0.96 per percentage rise, 95% CI 0.95 to 0.98). Patients who had been added to a COPD register had a significantly higher clinical care score (mean difference 5.06, 95% CI 4.36 to 5.75).

conclusionsOnly one in five case-found patients had been registered with COPD. Patients added to a COPD register received significantly higher levels of appropriate clinical care. TRIAL REGISTRATION NUMBER: ISRCTN14930255; Post-results.

Indexed as

Pulmonary Disease, Chronic ObstructiveAdultAgedForced Expiratory VolumeHumansMiddle AgedPrimary Health CareProspective StudiesQuality of LifeSurveys and Questionnaireschronic airways diseaseprimary carepublic health

Identifiers

PMID33020099
PMCPMC7537458

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.