ArticleGlobal health action2020
Neurodevelopmental outcomes of preterm babies during infancy in Eastern Uganda: a prospective cohort study.
Article in Global health action, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.
- The association of breastfeeding with cognitive development and educational achievement in sub-Saharan Africa: A systematic review.Journal of global health · 2022Pooled it
- Growth and neurodevelopmental outcomes of preterm and low birth weight infants in rural Kenya: a cross-sectional study.BMJ open · 2023Trial
- Health Workers' Knowledge and Practice of Developmentally Supportive Care for Premature Infants in Four Ugandan Neonatal Units: A Cross-Sectional Study.Health science reports · 2026Article
- Neurodevelopmental outcomes at 3-12 months corrected age in predominantly enteral-fed very low birth weight infants in a resource-limited South African setting.Frontiers in pediatrics · 2026Article
- Two-Year Longitudinal Motor Performance of Very Preterm and/or Very-Low-Birth-Weight Infants in Suriname.Children (Basel, Switzerland) · 2025Article
- Neurodevelopmental delay and associated factors among preterm infants aged 6 to 24 months adjusted gestation age in two urban hospitals in Uganda.PLOS global public health · 2025Article
- Survive and Thrive: Outcomes of Children Enrolled in a Follow-Up Clinic for Small and Sick Newborns in Rural Rwanda.Healthcare (Basel, Switzerland) · 2024Article
- Neurodevelopment assessment of small for gestational age children in a community-based cohort from Pakistan.Archives of disease in childhood · 2023Article
- High Burden of Neurodevelopmental Delay among Children Born to Women with Obstructed Labour in Eastern Uganda: A Cohort Study.International journal of environmental research and public health · 2023Article
- A Scoping Review of Preterm Births in Sub-Saharan Africa: Burden, Risk Factors and Outcomes.International journal of environmental research and public health · 2022Article
- Health facility readiness to care for high risk newborn babies for early childhood development in eastern Uganda.BMC health services research · 2022Article
- A Birth Cohort Study of Neurodevelopmental Outcomes from Birth to 2 Years of Age in Preterm Infants under 34 Weeks of Gestation.Journal of healthcare engineering · 2022Article
- Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundComplications due to prematurity are a threat to child survival and full developmental potential particularly in low-income settings.
objectiveThe aim of the study was to determine the neurodevelopmental outcomes among preterm infants and identify any modifiable factors associated with neurodevelopmental disability (NDD).
methodsWe recruited 454 babies (242 preterms with birth weight <2.5 kg, and 212 term babies) in a cohort study at birth from Iganga hospital between May and July 2018. We followed up the babies at an average age of 7 months (adjusted for prematurity) and assessed 211 preterm and 187 term infants for neurodevelopmental outcomes using the Malawi Developmental Assessment tool. Mothers were interviewed on care practices for the infants. Data were analyzed using STATA version 14.
resultsThe study revealed a high incidence of NDD of 20.4% (43/211) among preterm infants compared to 7.5% (14/187) among the term babies, p < 0.001, of the same age. The most affected domain was fine motor (11.8%), followed by language (9.0%). At multivariate analysis, malnutrition and Kangaroo Mother Care (KMC) at home after discharge were the key factors that were significantly associated with NDD among preterm babies. The prevalence of malnutrition among preterm infants was 20% and this significantly increased the odds of developing NDD, OR = 2.92 (95% CI: 1.27-6.71). KMC practice at home reduced the odds of developing NDD, OR = 0.46, (95% CI: 0.21-1.00). Re-admission of preterm infants after discharge (a sign of severe illness) increased the odds of developing NDD but this was not statistically significant, OR = 2.33 (95% CI: 0.91-5.94).
conclusionOur study has shown that preterm infants are at a high risk of developing NDD, especially those with malnutrition. Health system readiness should be improved to provide follow-up care with emphasis on improving nutrition and continuity of KMC at home.
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