Evidence map›Paper›PMID 33019624›Full record

ArticleViruses2020

Electrostatic Surface Properties of Blood and Semen Extracellular Vesicles: Implications of Sialylation and HIV-Induced Changes on EV Internalization.

Hussein Kaddour, Tyler D Panzner, Jennifer L Welch, Nadia Shouman, Mahesh Mohan, Jack T Stapleton, Chioma M Okeoma

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 36 citations in OpenAlex.

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  9. Exploring the Proteomic Landscape and Immunomodulatory Functions ofJournal of microbiology and biotechnology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Hussein KaddourDepartment of Pharmacology, Stony Brook University Renaissance School of Medicine, Stony Brook, NY 11794, USA.ORCID 0000-0002-4371-0809
Tyler D PanznerDepartment of Pharmacology, Stony Brook University Renaissance School of Medicine, Stony Brook, NY 11794, USA.ORCID 0000-0002-2057-7427
Jennifer L WelchDepartment of Microbiology and Immunology, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA.ORCID 0000-0003-2725-9875
Nadia ShoumanDepartment of Pharmacology, Stony Brook University Renaissance School of Medicine, Stony Brook, NY 11794, USA.
Mahesh MohanHost Pathogen Interaction Program, Southwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, TX 78227, USA.ORCID 0000-0003-4360-3277
Jack T StapletonDepartment of Microbiology and Immunology, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA.ORCID 0000-0002-2302-9055
Chioma M OkeomaDepartment of Pharmacology, Stony Brook University Renaissance School of Medicine, Stony Brook, NY 11794, USA.ORCID 0000-0001-7737-6493
Stony Brook School · USUniversity of Iowa · USTexas Biomedical Research Institute · US

Funding

Training Program in Pharmacological SciencesT32GM007518 · NIGMS · STATE UNIVERSITY NEW YORK STONY BROOK · PI GARCIA-DIAZ, MIGUEL · 1985 to 2021
$5.4M
RESEARCH TRAINING IN INFECTIOUS DISEASEST32AI007343 · NIAID · UNIVERSITY OF IOWA · PI STAPLETON, JACK T. · 1988 to 2024
$5.0M
Cannabinoid modulation of EV composition and function in HIV/SIV infectionR01DA050169 · NIDA · STATE UNIVERSITY NEW YORK STONY BROOK · PI MOHAN, MAHESH, OKEOMA, CHIOMA M · 2019 to 2023
$3.8M
The effect of HIV and cocaine abuse on semen exosome composition and functionR01DA042348 · NIDA · UNIVERSITY OF IOWA · PI OKEOMA, CHIOMA M · 2016 to 2020
$2.7M
BLRD VA I01 BX000207NIAID NIH HHS T32 AI007343NIDA NIH HHS DA042348NIDA NIH HHS DA050169NIDA NIH HHS R01 DA042348NIDA NIH HHS R01 DA050169NIGMS NIH HHS T32 GM007518
6 · The paper itself

Abstract

Although extracellular vesicle (EV) surface electrostatic properties (measured as zeta potential, ζ-potential) have been reported by many investigators, the biophysical implications of charge and EV origin remains uncertain. Here, we compared the ζ-potential of human blood EVs (BEVs) and semen EVs (SEVs) from 26 donors that were HIV-infected (HIV+,

Indexed as

Static ElectricityVirus InternalizationBloodCell CommunicationCell LineEpithelial CellsExtracellular VesiclesGlycocalyxHIVHIV InfectionsHumansMonocytesNeuraminidaseSemenSurface PropertiesNeuraminidasebiological membranesbloodextracellular vesiclesglycocalyxHIV-1semenzeta potential

Identifiers

PMID33019624
PMCPMC7601085
OpenAlexW3089606399

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.