Evidence map›Paper›PMID 33019623›Full record

ArticleMolecules (Basel, Switzerland)2020

Induction of Redox-Mediated Cell Death in ER-Positive and ER-Negative Breast Cancer Cells by a Copper(II)-Phenolate Complex: An In Vitro and In Silico Study.

Vaiyapuri Subbarayan Periasamy, Anvarbatcha Riyasdeen, Venugopal Rajendiran, Mallayan Palaniandavar, Hanumanthappa Krishnamurthy, Ali Abdullah Alshatwi, Mohammad Abdulkader Akbarsha

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 19 citations in OpenAlex.

  1. Cuproptosis: potential new direction in liver-related diseases research and treatment.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Vaiyapuri Subbarayan PeriasamyDepartment of Animal Science, Bharathidasan University, Tiruchirappalli 620024, India.
Anvarbatcha RiyasdeenDepartment of Animal Science, Bharathidasan University, Tiruchirappalli 620024, India.
Venugopal RajendiranDepartment of Chemistry, School of Basic and Applied Sciences, Central University of Tamil Nadu, Thiruvarur 610005, India.ORCID 0000-0003-2561-8387
Mallayan PalaniandavarDepartment of Chemistry, Bharathidasan University, Tiruchirappalli 620024, India.
Hanumanthappa KrishnamurthyNational Centre for Biological Sciences, Tata Institute for Fundamental Research, Bangalore 560065, India.
Ali Abdullah AlshatwiDepartment of Food and Nutrition, College of Food and Agricultural Sciences, King Saud University, P.O. Box 2460, Riyadh 11451, Saudi Arabia.
Mohammad Abdulkader AkbarshaMahatma Gandhi-Doerenkamp Center (MGDC) for Alternatives to Use of Animals in Life Science Education, Bharathidasan University, Tiruchirappalli 620024, India.
Bharathidasan University · INKing Saud University · SACentral University of Tamil Nadu · INNational Centre for Biological Sciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This research was aimed at finding the cytotoxic potential of the mixed ligand copper(II) complex [Cu(tdp)(phen)](ClO

Indexed as

Computer SimulationBreast NeoplasmsCell CycleCell DeathCell Line, TumorComet AssayCopperDNA Breaks, Double-StrandedDNA DamageDNA, NeoplasmFemaleFluorescenceHumansHydroxybenzoatesMembrane Potential, MitochondrialMolecular Docking SimulationCopperDNA, NeoplasmHydroxybenzoatesphenolic acidReactive Oxygen SpeciesReceptors, Estrogenanticancer agentsapoptosisbreast cancercell cycle arrestcopper(II)-phenolate complexnecrosisROS

Identifiers

PMID33019623
PMCPMC7583785
OpenAlexW3090908137

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.