Evidence map›Paper›PMID 33019606›Full record

ArticleMolecules (Basel, Switzerland)2020

Safety of Concentrated Bioshell Calcium Oxide Water Application for Surface and Skin Disinfections against Pathogenic Microbes.

Masayuki Ishihara, Yuuki Hata, Sumiyo Hiruma, Tomohiro Takayama, Shingo Nakamura, Yoko Sato, Naoko Ando, Koichi Fukuda, Kaoru Murakami, Hidetaka Yokoe

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Oyster Shell Modified Tobacco Straw Biochar: Efficient Phosphate Adsorption at Wide Range of pH Values.International journal of environmental research and public health · 2022
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Masayuki IshiharaDivision of Biomedical Engineering, National Defense Medical College Research Institute, 3-2 Namiki, Tokorozawa, Saitama 359-8513, Japan.
Yuuki HataDivision of Biomedical Engineering, National Defense Medical College Research Institute, 3-2 Namiki, Tokorozawa, Saitama 359-8513, Japan.ORCID 0000-0003-1493-1896
Sumiyo HirumaDivision of Biomedical Engineering, National Defense Medical College Research Institute, 3-2 Namiki, Tokorozawa, Saitama 359-8513, Japan.
Tomohiro TakayamaDepartment of Oral and Maxillofacial Surgery, National Defense Medical College Hospital, 3-2 Namiki, Tokorozawa, Saitama 359-8513, Japan.
Shingo NakamuraDivision of Biomedical Engineering, National Defense Medical College Research Institute, 3-2 Namiki, Tokorozawa, Saitama 359-8513, Japan.ORCID 0000-0001-6084-0958
Yoko SatoDivision of Statistical Analysis, Research Support Center, Shizuoka General Hospital, 4-27-1 Kita-ando, Aoi-ku, Shizuoka 420-8527, Japan.ORCID 0000-0001-8123-5191
Naoko AndoDivision of Biomedical Engineering, National Defense Medical College Research Institute, 3-2 Namiki, Tokorozawa, Saitama 359-8513, Japan.
Koichi FukudaDivision of Biomedical Engineering, National Defense Medical College Research Institute, 3-2 Namiki, Tokorozawa, Saitama 359-8513, Japan.
Kaoru MurakamiDepartment of Oral and Maxillofacial Surgery, National Defense Medical College Hospital, 3-2 Namiki, Tokorozawa, Saitama 359-8513, Japan.
Hidetaka YokoeDepartment of Oral and Maxillofacial Surgery, National Defense Medical College Hospital, 3-2 Namiki, Tokorozawa, Saitama 359-8513, Japan.
National Defense Medical College · JPNational Defense Medical College Hospital · JPShizuoka General Hospital · JP

Funding

Japan Society for the Promotion of Science JP19K15955
6 · The paper itself

Abstract

Immediately post-production, commercially available bioshell calcium oxide (BiSCaO) water is colorless, transparent, and strongly alkaline (pH 12.8), and is known to possess deodorizing properties and broad microbicidal activity. However, BiSCaO Water may represent a serious safety risk to the living body, given the strong alkalinity. This study aimed to investigate the safety of BiSCaO Water for use as an antiseptic/disinfectant despite concerns regarding its high alkalinity. The change over time in pH of BiSCaO Water was measured during air contact (stirring BiSCaO Water in ambient air). When sprayed on metal, plastic, wood piece, paper, and skin surfaces, the pH of BiSCaO Water decreased rapidly, providing a white powder coating upon drying. Scanning electron microscopy images, energy dispersive X-ray elemental mapping, and X-ray diffractograms showed that the dried powder residues of BiSCaO Water were composed primarily of calcium carbonate. These results suggested that BiSCaO Water is a potent reagent that may overcome the obstacles of being strongly alkaline, making this material appropriate for use in disinfection against pathogenic microbes.

Indexed as

DisinfectionAnimalsBiocompatible MaterialsCalcium CompoundsColloidsHydrogen-Ion ConcentrationMicroscopy, Electron, ScanningOxidesPowdersRats, HairlessSkinSpectrometry, X-Ray EmissionSuspensionsWaterWoodX-Ray DiffractionBiocompatible MaterialsCalcium CompoundsColloidslimeOxidesPowdersSuspensionsWaterbioshell calcium oxidescalcium carbonatedisinfectantmicrobicidal activitysafetystrong alkalinity

Identifiers

PMID33019606
PMCPMC7582750
OpenAlexW3091726580

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.