Evidence map›Paper›PMID 33019598›Full record

ReviewInternational journal of molecular sciences2020

Focus on UV-Induced DNA Damage and Repair-Disease Relevance and Protective Strategies.

Mateusz Kciuk, Beata Marciniak, Mariusz Mojzych, Renata Kontek

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

75 citing papers in PubMed, 141 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. The cutaneous microbiome as a dynamic photoprotective interface against solar radiation.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2026
    Review
  11. Article
  12. Article
  13. Comparative analysis of wavelength-specific UV stress granule formation.bioRxiv : the preprint server for biology · 2026
    Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. DNA Damage and Repair in Pancreatic Cancer-The Latest Findings.International journal of molecular sciences · 2025
    Review
  19. Article
  20. Article

15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Mateusz KciukDoctoral School of Exact and Natural Sciences, University of Lodz, Banacha Street 12/16, 90-237 Lodz, Poland.ORCID 0000-0002-8616-3825
Beata MarciniakDepartment of Molecular Biotechnology and Genetics, Faculty of Biology and Environmental Protection, University of Lodz, 12/16 Banacha St., 90-237 Lodz, Poland.ORCID 0000-0001-8109-6478
Mariusz MojzychDepartment of Chemistry, Siedlce University of Natural Sciences and Humanities, 3 Maja 54, 08-110 Siedlce, Poland.ORCID 0000-0002-9884-6068
Renata KontekDepartment of Molecular Biotechnology and Genetics, Faculty of Biology and Environmental Protection, University of Lodz, 12/16 Banacha St., 90-237 Lodz, Poland.ORCID 0000-0003-2859-9839
University of Łódź · PLUniversity of Siedlce · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The protective ozone layer is continually depleting due to the release of deteriorating environmental pollutants. The diminished ozone layer contributes to excessive exposure of cells to ultraviolet (UV) radiation. This leads to various cellular responses utilized to restore the homeostasis of exposed cells. DNA is the primary chromophore of the cells that absorbs sunlight energy. Exposure of genomic DNA to UV light leads to the formation of multitude of types of damage (depending on wavelength and exposure time) that are removed by effectively working repair pathways. The aim of this review is to summarize current knowledge considering cellular response to UV radiation with special focus on DNA damage and repair and to give a comprehensive insight for new researchers in this field. We also highlight most important future prospects considering application of the progressing knowledge of UV response for the clinical control of diverse pathologies.

Indexed as

Ataxia Telangiectasia Mutated ProteinsCell CycleCheckpoint Kinase 1DNADNA DamageDNA RepairEscherichia coliGene Expression RegulationHumansMitogen-Activated Protein KinasesPyrimidine DimersSignal TransductionStratospheric OzoneSunlightUltraviolet RaysAtaxia Telangiectasia Mutated ProteinsATM protein, humanATR protein, humanCheckpoint Kinase 1CHEK1 protein, humanDNAMitogen-Activated Protein KinasesPyrimidine Dimerspyrimidine-pyrimidone dimerStratospheric OzoneDNA damageDNA repairphotoproductsROSUV radiation

Identifiers

PMID33019598
PMCPMC7582305
OpenAlexW3089657300

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.