Observational studyMedicine2020
Clinical characteristics of pneumoperitoneum with pneumatosis intestinalis detected using computed tomography: A descriptive study.
Observational study in Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 18 citations in OpenAlex.
- Non-Surgical Pneumoperitoneum After Fenestrated Endovascular Aortic Repair- Case Report.Vascular and endovascular surgery · 2026Article
- Pneumatosis intestinalis revisited: associated imaging findings, clinical correlation, management, risk stratification and future perspectives.Emergency radiology · 2026Review
- Idiopathic pneumoperitoneum: two cases with possible association to elevated intraluminal pressure.International journal of emergency medicine · 2026Article
- Multi-slice computed tomography diagnosis of pneumatosis cystoides intestinalis with pneumoperitoneum in high-altitude regions: preventing unnecessary laparotomies.Quantitative imaging in medicine and surgery · 2026Article
- Recurrent pneumoperitoneum with pneumatosis cystoides intestinalis in tuberculous pleurisy: Case report.Medicine · 2025Article
- Persistent Asymptomatic Pneumoperitoneum With Spontaneously Resolving Idiopathic Pneumatosis Intestinalis: A Case Report.Case reports in surgery · 2025Article
- Systemic lupus erythematosus presenting with pneumoperitoneum without evidence of pneumatosis cystoides intestinalis-when not to operate-a case report.Journal of surgical case reports · 2024Article
- Incidental pneumoperitoneum due to pneumatosis intestinalis: A rare case of benign pneumoperitoneum.International journal of surgery case reports · 2024Article
- The Challenge of Pneumatosis Intestinalis: A Contemporary Systematic Review.Journal of personalized medicine · 2024Review
- The spectrum of pneumatosis intestinalis in the adult. A surgical dilemma.World journal of gastrointestinal surgery · 2023Review
- Pneumatosis Intestinalis Developed in a Patient with Giant Cell Arteritis While in a Clinically Sustained Remission Phase.Internal medicine (Tokyo, Japan) · 2022Article
- Idiopathic asymptomatic pneumoperitoneum in a patient with ureteric calculus and Crohn's disease.Journal of surgical case reports · 2022Article
- Idiopathic Nonsurgical Pneumoperitoneum in Healthy Individuals after Endoscopy: Coincidence or Consequence?Case reports in gastrointestinal medicine · 2022Article
- Asymptomatic pneumoperitoneum or pneumatosis cystoides intestinalis? Easy to make a mistake.Journal of surgical case reports · 2021Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pneumoperitoneum has always been considered a surgical emergency as it represents a perforation of the gastrointestinal tract. Although several cases of pneumoperitoneum with pneumatosis intestinalis (PI) have been reported, the characteristics of such cases remain unclear. The current study aimed to clarify the clinical characteristics of pneumoperitoneum cases with PI detected using computed tomography (CT).This descriptive study was conducted at a single center. In a total of 18,513 abdominal CT scans obtained between January 2010 and February 2017, extraluminal free air was detected in 254 examinations of 182 cases. The medical records and CT images of these 182 patients were retrospectively analyzed.Pneumoperitoneum with PI was detected through 23 examinations in 21 cases, and the average age of the patients was 80.1 years. The frequency was 0.12% in all abdominal CT examinations, but 24.7% in the 85 cases with extraluminal free air, excluding iatrogenic air. PI was classified as benign in 20 cases and as life-threatening in 1 case. The majority of cases with benign PI showed good general and local findings and little leukocytosis, while the case with life-threatening PI showed severe conditions. No evidence of bowel wall discontinuity, segmental bowel-wall thickening, perivisceral fat stranding, and abscesses were observed. Ascites were detected less frequently in the cases with PI than in the other pneumoperitoneum cases (P < .01). Pneumoperitoneum and PI occasionally recurred, and PI and/or extraluminal free air generally disappeared quickly.Pneumoperitoneum with PI is a relatively common condition in older patients, and the majority of cases are caused by benign PI. The characteristics of pneumoperitoneum cases with benign PI include well-maintained physical conditions, normal laboratory data, absence of CT findings indicative of peritonitis, and infrequent ascites. In pneumoperitoneum cases with PI, predicting whether the PI is benign or life-threatening is clinically very important, whereas the presence of extraluminal free air is considered to be insignificant.
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