Evidence map›Paper›PMID 33019404›Full record

ArticleMedicine2020

Survival analysis of patients with primary gallbladder cancer from 2010 to 2015: A retrospective study based on SEER data.

Xiaolei Zhu, Xiaochang Zhang, Xiao Hu, Hongyan Ren, Shenghui Wu, Jing Wu, Guoyi Wu, Xiang Si, Baohua Wang

Open access · goldAbstract read
In one paragraph

Article in Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

  1. Diagnostic performance and safety of endoscopic ultrasound-guided tissue acquisition of gallbladder lesions: A systematic review with meta-analysis.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2023
    Pooled it
  2. Article
  3. Article
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  5. Review
  6. Review
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  9. International collaborative research to improve gallbladder cancer prevention.Nature reviews. Gastroenterology & hepatology · 2025
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  10. Review
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  12. Review
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  14. Article
  15. Article
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  18. Frontiers in genetics · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

Xiaolei ZhuOffice of Noncommunicable Disease Control and Aging Health, Chinese Center for Disease Control and Prevention.ORCID 0000-0002-1024-3538
Xiaochang ZhangOffice of Noncommunicable Disease Control and Aging Health, Chinese Center for Disease Control and Prevention.
Xiao HuInformation Center, Beijing Center for Disease Control and Prevention, Beijing, China.
Hongyan RenInstitute of Geographic Sciences and Natural Resources Research, Chinese Academy of Sciences.
Shenghui WuDepartment of Epidemiology and Biostatistics, University of Texas Health San Antonio, San Antonio, TX.
Jing WuNational Center for Chronic and Noncommunicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing.
Guoyi WuShanghai Public Health Clinical Center, Fudan University, 2901 Caolang Road, Jin Shan District, Shanghai, China.
Xiang SiOffice of Noncommunicable Disease Control and Aging Health, Chinese Center for Disease Control and Prevention.
Baohua WangNational Center for Chronic and Noncommunicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing.
Center for Disease Control · TWBeijing Center for Disease Prevention and Control · CNChinese Academy of Sciences · CNNational Center for Chronic and Noncommunicable Disease Control and Prevention · CNThe University of Texas Health Science Center at San Antonio · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aims to assess the survival status of patients with Primary gallbladder cancer (PGC) and analyze the prognosis factors to facilitate the exploration of the prevention and therapeutic strategies of PGC.Data from 2433 PGC patients collected from 2010 to 2015 were extracted from the Surveillance, Epidemiology, and End Results (SEER) database. The SEER*Stat, SPSS 23.0 and GraphPad Prism 8 were used for statistical analyses. Kaplan Meier analysis was performed for the survival curve, log-rank test analyses were used to compare the survival rate difference and Cox regression analyses were performed to determine the prognosis factors.A total of 2433 PGC cases were reported from 2010 to 2015. The median age was 64.2 ± 10.4 years old and the percentages of the white patients were 73.7% (1794/2433). The percentage of patients who received surgery treatment was 82.1% (1998/2433). The overall median survival time of all patients was 19 months and the 5-year survival rate was 28.8%. The 5-year survival rate of PGC patients in pN2 stage dropped to 0% and the 5-year survival rate for PGC patients with distant metastasis was only 2.7%. Age, tumor size, grade, pT stage, pM stage were risk factors for prognosis, surgery or not and radiation or not were protective factors for prognosis.Survival analysis of PGC patients based on the SEER database have provided an opportunity for understanding PGC prognosis and the basis for the exploration of viable PGC prevention and therapeutic strategies.

Indexed as

AgedFemaleGallbladder NeoplasmsHumansKaplan-Meier EstimateMaleMiddle AgedMultivariate AnalysisNeoplasm GradingPrognosisRetrospective StudiesRisk FactorsSEER ProgramSocioeconomic FactorsTumor Burden

Identifiers

PMID33019404
PMCPMC7535694
OpenAlexW3090404330

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.