SynthesisMedicine2020
Does time of day influences outcome in out-of-hospital cardiac arrest patients?: A meta-analysis of cohort studies.
Synthesis in Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
6 citing papers in PubMed.
- "When" matters: Differences in fatal opioid-related overdose events in Massachusetts by time of day, 2019-2023.Drug and alcohol dependence · 2026Article
- Functional Access to Public Defibrillators and Out-of-Hospital Cardiac Arrest Outcomes: A Population-Based Geospatial Analysis in Korea.Journal of the American Heart Association · 2026Article
- Wearable devices for out-of-hospital cardiac arrest: A population survey on the willingness to adhere.Journal of the American College of Emergency Physicians open · 2024Article
- Measurement of thalamus and cortical damages in hypoxic ischemic encephalopathy.IBRO neuroscience reports · 2023Article
- Rapid-cycle deliberate practice versus after-event debriefing clinical simulation in cardiopulmonary resuscitation: a cluster randomized trial.Advances in simulation (London, England) · 2022Article
- Effect of Temporal Difference on Clinical Outcomes of Patients with Out-of-Hospital Cardiac Arrest: A Retrospective Study from an Urban City of Taiwan.International journal of environmental research and public health · 2021Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWhether time of day has impact on outcomes after out-of-hospital cardiac arrest (OHCA) remains controversial. However, there are no evidence syntheses describing the impact of time differences on outcomes from OHCA.
methodsA meta-analysis of cohort studies exploring the association between time of day and survival in patients with OHCA was performed. Odds ratios (ORs) with 95% confidence intervals (CIs) were pooled using a random-effects model.
resultsTen studies involving 252,848 patients and 24,646 survivals were included. Patients with night-time OHCA had significantly lower short-term survival compared to patients with daytime OHCA (OR, 1.20; 1.07-1.36; P < .001). The relationship between temporal differences and survival was consistent in most subgroups. For long-term survival, it remained unclear whether night-time was associated with reduced OHCA survival at 12 months (OR, 1.47; 0.71-3.06; P < .001). Three studies including 183,129 patients examined the association between weekend and survival in OHCA patients. Survival did not differ on weekends compared to weekdays (OR, 1.00; 0.9 7-1.04; P = .918).
conclusionsNight-time is associated with a lower survival in OHCA patients. However, similar findings are not observed in OHCA patients on weekends. Caution is required in interpretation of these results accounting for high level of heterogeneity and large, well designed, randomized trials are warranted.
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