ArticleMagnetic resonance in medicine2021
Myelin water imaging depends on white matter fiber orientation in the human brain.
Article in Magnetic resonance in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
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Who cites it
40 citing papers in PubMed, 76 citations in OpenAlex.
- Unifying orientation-dependent relaxation and diffusion around axonal fibers in DTI: characterizing fiber-tract-specific anisotropic RBrain structure & function · 2026Article
- Axon Diameter Mapping From Myelin Water Diffusion MRI.IEEE transactions on medical imaging · 2026Article
- Field Strength-Dependent White Matter RMagnetic resonance in medicine · 2026Article
- MC BTS: Simultaneously Resolving Magnetization Transfer Effect and Relaxation for Multiple Components.Magnetic resonance in medicine · 2026Article
- The Impact of Gadolinium on Quantitative Myelin Metrics in Ex Vivo Spinal Cord.NMR in biomedicine · 2026Article
- Multi-contrast dual-resolution UTE for myelin fraction mapping and structural imaging.Magma (New York, N.Y.) · 2026Article
- Axonal microstructure and compartmentalization impact the orientation and time dependence of mesoscopic transverse relaxation.Scientific reports · 2026Article
- Intraoperative 3D quantitative magnetic resonance imaging in paediatric brain tumour surgery.PloS one · 2026Article
- Imaging markers of neuroinflammation in aging and Alzheimer's disease and related dementia: A comprehensive review.Neuroscience and biobehavioral reviews · 2025Review
- Unraveling the major role of vascular (R2') contributions to R2* signal relaxation at ultra-high-field MRI: A comprehensive analysis with quantitative gradient recalled echo in mouse brain.Magnetic resonance in medicine · 2025Article
- Quantum magnetization exchange through transient hydrogen bond matrix defines magnetic resonance signal relaxation and anisotropy in central nervous system.Scientific reports · 2025Article
- The relationship of white matter tract orientation to vascular geometry in the human brain.Scientific reports · 2025Article
- The relationship of white matter tract orientation to vascular geometry in the human brain.bioRxiv : the preprint server for biology · 2025Article
- An unconstrained four pool model analysis of proton relaxation and magnetization transfer in ex vivo white matter.Scientific reports · 2025Article
- Interplay between MRI-based axon diameter and myelination estimates in macaque and human brain.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- High-resolution quantitative TImaging neuroscience (Cambridge, Mass.) · 2025Article
- Harnessing myelin water fraction as an imaging biomarker of human cerebral aging, neurodegenerative diseases, and risk factors influencing myelination: A review.Journal of neurochemistry · 2024Review
- The myelin water imaging transcriptome: myelin water fraction regionally varies with oligodendrocyte-specific gene expression.Molecular brain · 2024Article
- Circadian rapid eye movement sleep expression is associated with brain microstructural integrity in older adults.Communications biology · 2024Article
- Anisotropic longitudinal water proton relaxation in white matter investigated ex vivo in porcine spinal cord with sample rotation.Scientific reports · 2024Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 3 countries.
Funding
Abstract
purposeThe multi-exponential T
methodsMaps of the apparent MWF were acquired using multi-echo Carr-Purcell-Meiboom-Gill and gradient-echo spin-echo sequences. The Carr-Purcell-Meiboom-Gill sequence was acquired with a TR of 1073 ms, 1500 ms, and 2000 ms. The fiber orientation was mapped with DTI. By angle-wise pooling the voxels across the brain's white matter, orientation-dependent apparent MWF curves were generated.
resultsWe found that the apparent MWF varied between 25% and 35% across different fiber orientations. Furthermore, the selection of the TR influences the apparent MWF.
conclusionWhite matter fiber orientation induces a strong systematic bias on the estimation of the apparent MWF. This finding has implications for future research and the interpretation of MWI results in previously published studies.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.