Trial reportCirculation2020
National Variation in Congenital Heart Surgery Outcomes.
Trial report in Circulation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed.
- Randomized Trial of Pulsatile and Nonpulsatile Flow in Cyanotic and Acyanotic Congenital Heart Surgery.World journal for pediatric & congenital heart surgery · 2025Trial
- Impact of Neighborhood and Individual Social Drivers of Health on Outcomes Following Congenital Heart Surgery.World journal for pediatric & congenital heart surgery · 2026Article
- Implementation and Results of Intraoperative Methadone in Pediatric Cardiac Surgery: Early Experiences and Outcomes.World journal for pediatric & congenital heart surgery · 2026Article
- Machine Learning Model for Predicting Postoperative Complications in Pediatric Simple Congenital Heart Disease with Right Vertical Infra-Axillary Incision.Journal of cardiovascular development and disease · 2026Article
- Determinants of Early Mortality After Congenital Heart Surgery: A 7-Year Single-center Experience in Saudi Arabia.Journal of the Saudi Heart Association · 2026Article
- Immune Unresponsiveness to Cardiopulmonary Bypass Is Associated With Unfavorable Outcome in Infants Requiring Cardiac Surgery.JACC. Basic to translational science · 2026Article
- Total Tau protein as a novel biomarker for detection of neural injury following cardiopulmonary bypass in pediatric congenital heart surgery patients.JTCVS open · 2025Article
- Consensus on Key Attributes of Cardiac Surgeons' Intraoperative Performance.Journal of surgical education · 2025Article
- Will your next surgeon be a robot? Autonomy and AI in robotic surgery.Science robotics · 2025Review
- Persistent Imbalance: Women's Representation in North American Pediatric Cardiology Leadership Roles.JACC. Advances · 2025Article
- The Role of Extracellular-Vesicle-Derived miRNAs in Postoperative Organ Dysfunction in Neonates and Infants Undergoing Congenital Cardiac Surgery: An Exploratory Study.International journal of molecular sciences · 2025Article
- Evaluating Long-Term Outcomes of Children Undergoing Surgical Treatment for Congenital Heart Disease for National Audit in England and Wales.Journal of the American Heart Association · 2024Article
- Incidence, risk factors, and outcomes of chylothorax after cardiac procedure in the United States.Heliyon · 2024Article
- Preclinical Proof-of-Concept of a Minimally Invasive Direct Cardiac Compression Device for Pediatric Heart Support.Cardiovascular engineering and technology · 2024Article
- Association of preoperative retinal microcirculation and perioperative outcomes in patients undergoing congenital cardiac surgery.Orphanet journal of rare diseases · 2023Observational
- Adjusting for Congenital Heart Surgery Risk Using Administrative Data.Journal of the American College of Cardiology · 2023Article
- Asymptotic Properties for Cumulative Probability Models for Continuous Outcomes.Mathematics (Basel, Switzerland) · 2023Article
- Article
- Toward a Roadmap for Best Practices in Pediatric Preventive Cardiology: A Science Advisory From the American Heart Association.Circulation. Cardiovascular quality and outcomes · 2023Review
- Procedure-Specific Center Volume and Mortality After Infantile Congenital Heart Surgery.The Annals of thoracic surgery · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
Abstract
backgroundOptimal strategies to improve national congenital heart surgery outcomes and reduce variability across hospitals remain unclear. Many policy and quality improvement efforts have focused primarily on higher-risk patients and mortality alone. Improving our understanding of both morbidity and mortality and current variation across the spectrum of complexity would better inform future efforts.
methodsHospitals participating in the Society of Thoracic Surgeons Congenital Heart Surgery Database (2014-2017) were included. Case mix-adjusted operative mortality, major complications, and postoperative length of stay were evaluated using Bayesian models. Hospital variation was quantified by the interdecile ratio (IDR, upper versus lower 10%) and 95% credible intervals (CrIs). Stratified analyses were performed by risk group (Society of Thoracic Surgeons-European Association for Cardiothoracic Surgery [STAT] category) and simulations evaluated the potential impact of reductions in variation.
resultsA total of 102 hospitals (n=84 407) were included, representing ≈85% of US congenital heart programs. STAT category 1 to 3 (lower risk) operations comprised 74% of cases. All outcomes varied significantly across hospitals: adjusted mortality by 3-fold (upper versus lower decile 5.0% versus 1.6%, IDR 3.1 [95% CrI 2.5-3.7]), mean length of stay by 1.8-fold (19.2 versus 10.5 days, IDR 1.8 [95% CrI 1.8-1.9]), and major complications by >3-fold (23.5% versus 7.0%, IDR 3.4 [95% CrI 3.0-3.8]). The degree of variation was similar or greater for low- versus high-risk cases across outcomes, eg, ≈3-fold mortality variation across hospitals for STAT 1 to 3 (IDR 3.0 [95% CrI 2.1-4.2]) and STAT 4 or 5 (IDR 3.1 [95% CrI 2.4-3.9]) cases. High-volume hospitals had less variability across outcomes and risk categories. Simulations suggested potential reductions in deaths (n=282), major complications (n=1539), and length of stay (101 183 days) over the 4-year study period if all hospitals were to perform at the current median or better, with 37% to 60% of the improvement related to the STAT 1 to 3 (lower risk) group across outcomes.
conclusionsWe demonstrate significant hospital variation in morbidity and mortality after congenital heart surgery. Contrary to traditional thinking, a substantial portion of potential improvements that could be realized on a national scale were related to variability among lower-risk cases. These findings suggest modifications to our current approaches to optimize care and outcomes in this population are needed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.