Evidence map›Paper›PMID 33017176›Full record

ArticleEnvironmental health perspectives2020

Air Pollution and Progression of Atherosclerosis in Different Vessel Beds-Results from a Prospective Cohort Study in the Ruhr Area, Germany.

Frauke Hennig, Marie Henrike Geisel, Hagen Kälsch, Sarah Lucht, Amir Abbas Mahabadi, Susanne Moebus, Raimund Erbel, Nils Lehmann, Karl-Heinz Jöckel, André Scherag and 2 more

Open access · diamondAbstract read
In one paragraph

Article in Environmental health perspectives, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 29 citations in OpenAlex.

  1. Systematic review and meta-analysis on the health effects of long-term exposure to ultrafine particles.European respiratory review : an official journal of the European Respiratory Society · 2026
    Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Review
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  7. Article
  8. Article
  9. Long-term exposure to road traffic noise and stroke incidence: a Danish Nurse Cohort study.Environmental health : a global access science source · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 1 country.

Frauke HennigInstitute of Occupational, Social and Environmental Medicine, Center for Health and Society, Medical Faculty, Heinrich-Heine University Düsseldorf, Düsseldorf, Germany.
Marie Henrike GeiselInstitute for Medical Informatics, Biometry and Epidemiology, University Hospital, University Duisburg-Essen, Essen, Germany.
Hagen KälschDepartment of Cardiology, Alfried Krupp Hospital Essen, Essen, Germany.
Sarah LuchtInstitute of Occupational, Social and Environmental Medicine, Center for Health and Society, Medical Faculty, Heinrich-Heine University Düsseldorf, Düsseldorf, Germany.
Amir Abbas MahabadiDepartment of Cardiology and Vascular Medicine, West German Heart and Vascular Center, University Hospital Essen, Essen, Germany.
Susanne MoebusCenter of Urban Epidemiology (Cue), Institute for Medical Informatics, Biometry and Epidemiology, University Hospital Essen, Essen, Germany.
Raimund ErbelInstitute for Medical Informatics, Biometry and Epidemiology, University Hospital, University Duisburg-Essen, Essen, Germany.
Nils LehmannInstitute for Medical Informatics, Biometry and Epidemiology, University Hospital, University Duisburg-Essen, Essen, Germany.
Karl-Heinz JöckelInstitute for Medical Informatics, Biometry and Epidemiology, University Hospital, University Duisburg-Essen, Essen, Germany.
André ScheragResearch Group Clinical Epidemiology, Center for Sepsis Control and Care (CSCC), Jena University Hospital, Jena, Germany.
Barbara HoffmannInstitute of Occupational, Social and Environmental Medicine, Center for Health and Society, Medical Faculty, Heinrich-Heine University Düsseldorf, Düsseldorf, Germany.
Heinz Nixdorf Recall Study Investigative Group
Heinrich Heine University Düsseldorf · DEUniversity of Duisburg-Essen · DEJena University Hospital · DEInstitut für Medizinische Informatik, Biometrie und Epidemiologie · DEWest German Heart and Vascular Center Essen · DEWitten/Herdecke University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesDue to inconsistent epidemiological evidence on health effects of air pollution on progression of atherosclerosis, we investigated several air pollutants and their effects on progression of atherosclerosis, using carotid intima media thickness (cIMT), coronary calcification (CAC), and thoracic aortic calcification (TAC).

methodsWe used baseline (2000-2003) and 5-y follow-up (2006-2008) data from the German Heinz Nixdorf Recall cohort study, including 4,814 middle-aged adults. Residence-based long-term air pollution exposure, including particulate matter (PM) with aerodynamic diameter

resultsWhile no clear associations were observed in the full study sample (mean age 59.1 (

conclusionOur study suggests that development and progression of subclinical atherosclerosis is associated with long-term air pollution in middle-aged participants with no or minor atherosclerotic burden at baseline, while overall no consistent associations are observed. https://doi.org/10.1289/EHP7077.

Indexed as

AdultAir PollutantsAir PollutionAtherosclerosisCarotid Intima-Media ThicknessCohort StudiesDisease ProgressionEnvironmental ExposureFemaleGermanyHousingHumansMaleMiddle AgedNitrogen DioxideParticulate MatterAir PollutantsNitrogen DioxideParticulate Matter

Identifiers

PMID33017176
PMCPMC7535085
OpenAlexW3089583056

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.