Evidence map›Paper›PMID 33017121›Full record

Trial reportCornea2020

Corneal Scheimpflug Densitometry in Photorefractive Keratectomy Candidates.

Mojgan Pakbin, Mehdi Khabazkhoob, Mohammad Pakravan, Akbar Fotouhi, Ebrahim Jafarzadehpur, Mohamadreza Aghamirsalim, Hassan Hashemi

Abstract readClinical Trial
PubMed Publisher
In one paragraph

Trial report in Cornea, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Mojgan PakbinNoor Ophthalmology Research Center, Noor Eye Hospital, Tehran, Iran.
Mehdi KhabazkhoobDepartment of Medical Surgical Nursing, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Mohammad PakravanOphthalmic Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Akbar FotouhiDepartment of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran; and.
Ebrahim JafarzadehpurNoor Research Center for Ophthalmic Epidemiology, Noor Eye Hospital, Tehran.
Mohamadreza AghamirsalimTranslational Ophthalmology Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Hassan HashemiNoor Ophthalmology Research Center, Noor Eye Hospital, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo describe the normative data of corneal densitometry in photorefractive Keratectomy (PRK) candidates by using a Scheimpflug camera.

methodsFive hundred twenty-two eyes of 261 PRK candidates that underwent comprehensive optometric and ophthalmic examinations were enrolled in this study. Corneal densitometry values were obtained using a Scheimpflug camera (Pentacam HR; Oculus Optikgeräte GmbH, Wetzlar, Germany) and displayed in grayscale units (GSU).

resultsOf 261 participants, 187 (71.6%) were women. The mean age of the participants was 28.79 ± 5.02 years (range: 21-40 years). The mean entire corneal densitometry was 14.86 ± 2.37 GSU. According to corneal depth, maximum and minimum densitometry values were seen in the anterior (30.28 ± 7.42 GSU) and posterior (9.86 ± 2.08 GSU) layers, respectively (P < 0.001). Based on the annulus over the cornea, the highest and lowest densitometry values were seen in the 10- to 12-mm (21.31 ± 4.26 GSU) and 2- to 6-mm zones (13.26 ± 2.34 GSU), respectively. However, this difference was not seen after 35 years of age. Individuals aged 30 to 35 years showed higher corneal densitometry values compared with subjects aged 20 to 25 years old (P < 0.001). In generalized linear models, the corneal thickness was associated with the densitometry value in the central and posterior corneal layers. There were no significant differences in sex and refractive errors among participants.

conclusionsThis study provided normal corneal densitometry data in PRK candidates. Corneal densitometry increased with age until 35 years of age and then decreased thereafter. This finding should be considered in patient selection for PRK and their postoperative examinations.

Indexed as

Photorefractive KeratectomyAdultCorneaCorneal OpacityCross-Sectional StudiesDensitometryFemaleHumansMaleMyopiaPhotographyYoung Adult

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.