Evidence map›Paper›PMID 33016987›Full record

Trial reportJAMA pediatrics2020

Effectiveness of a Home- and School-Based Asthma Educational Program for Head Start Children With Asthma: A Randomized Clinical Trial.

Michelle N Eakin, Sandra Zaeh, Thomas Eckmann, Elizabeth Ruvalcaba, Cynthia S Rand, Marisa E Hilliard, Kristin A Riekert

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in JAMA pediatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01519453 (Reducing Asthma Morbidity in High Risk Minority Preschool Children), which is not on this map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01519453 nacompletednot on this map

Reducing Asthma Morbidity in High Risk Minority Preschool Children (Asthma Basic Care (ABC) at Head Start)

TypeinterventionalSponsorJohns Hopkins UniversityRan2011 to 2018Enrolled404ConditionsAsthmaArmsHome Based Asthma Education
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Home-based educational interventions for children with asthma.The Cochrane database of systematic reviews · 2025
    Pooled it
  2. Pooled it
  3. Review
  4. Review
  5. Individual and system-level determinants of caregivers' quality of life among inner-city preschool children with asthma.The Journal of asthma : official journal of the Association for the Care of Asthma · 2025
    Article
  6. Indoor bioaerosols and asthma: Overview, implications, and mitigation strategies.The Journal of allergy and clinical immunology · 2025
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Is there a best strategy to prevent asthma exacerbations in inner-city patients with asthma?Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2024
    Article
  12. Article
  13. Family management of asthma in Head Start preschool children.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2022
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Michelle N EakinDivision of Pulmonary and Critical Care Medicine, The Johns Hopkins University, Baltimore, Maryland.
Sandra ZaehDivision of Pulmonary and Critical Care Medicine, The Johns Hopkins University, Baltimore, Maryland.
Thomas EckmannDivision of Pulmonary and Critical Care Medicine, The Johns Hopkins University, Baltimore, Maryland.
Elizabeth RuvalcabaDivision of Pulmonary and Critical Care Medicine, The Johns Hopkins University, Baltimore, Maryland.
Cynthia S RandDivision of Pulmonary and Critical Care Medicine, The Johns Hopkins University, Baltimore, Maryland.
Marisa E HilliardDepartment of Pediatrics, Baylor College of Medicine and Texas Children's Hospital, Houston.
Kristin A RiekertDivision of Pulmonary and Critical Care Medicine, The Johns Hopkins University, Baltimore, Maryland.

Funding

Understanding the Impact of School Environment on Asthma Outcomes to Inform ImplementationF32HL149195 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI ZAEH, SANDRA · 2019 to 2020
$143k
NHLBI NIH HHS F32 HL149195
6 · The paper itself

Abstract

Importance: Asthma is the most common chronic childhood disease, with Black children experiencing worse morbidity and mortality. It is important to evaluate the effectiveness of efficacious interventions in community settings that have the greatest likelihood of serving at-risk families. Objective: To evaluate the effectiveness of a multilevel home- and school (Head Start)-based asthma educational program compared with a Head Start-based asthma educational program alone in improving asthma outcomes in children. Design, Setting, and Participant: This randomized clinical trial included 398 children with asthma enrolled in Head Start preschool programs in Baltimore, Maryland, and their primary caregivers. Participants were recruited from April 1, 2011, to November 31, 2016, with final data collection ending December 31, 2017. Data were analyzed from March 18 to August 30, 2018. Interventions: Asthma Basic Care (ABC) family education combined with Head Start asthma education compared with Head Start asthma education alone. Main Outcomes and Measures: Asthma control as measured by the Test for Respiratory and Asthma Control in Kids (TRACK) score. Results: Among the 398 children included in the analysis (247 boys [62.1%]; mean [SD] age, 4.2 [0.7] years), the ABC plus Head Start program improved asthma control (β = 6.26; 95% CI, 1.77 to 10.75; P < .001), reduced courses of oral corticosteroids (β = -0.61; 95% CI, -1.13 to -0.09; P = .02), and reduced hospitalizations (odds ratio, 0.36; 95% CI, 0.21-0.61; P < .001) during a 12-month period. Conclusion and Relevance: In this randomized clinical trial, combined family and preschool asthma educational interventions improved asthma control and reduced courses of oral corticosteroids and hospitalizations. Multilevel interventions implemented in community settings that serve low-income minority families may be key to reducing disparities in asthma outcomes. Trial Registration: ClinicalTrials.gov Identifier: NCT01519453.

Indexed as

Anti-Asthmatic AgentsAsthmaBaltimoreCaregiversChildChild, PreschoolEarly Intervention, EducationalFemaleHumansMalePatient Education as TopicProgram EvaluationSchool Health ServicesAnti-Asthmatic Agents

Identifiers

PMID33016987
PMCPMC7536623

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.