Evidence map›Paper›PMID 33016622›Full record

ArticleJournal of applied clinical medical physics2020

Single click automated breast planning with iterative optimization.

Ben Archibald-Heeren, Mikel Byrne, Yunfei Hu, Guilin Liu, Nick Collett, Meng Cai, Yang Wang

Open access · goldAbstract read
In one paragraph

Article in Journal of applied clinical medical physics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Ben Archibald-HeerenIcon Cancer Centres, Wahroonga, NSW, Australia.
Mikel ByrneIcon Cancer Centres, Wahroonga, NSW, Australia.
Yunfei HuIcon Cancer Centres, Wahroonga, NSW, Australia.
Guilin LiuIcon Cancer Centres, Wahroonga, NSW, Australia.
Nick CollettIcon Cancer Centres, Wahroonga, NSW, Australia.
Meng CaiIcon Cancer Centres, Wahroonga, NSW, Australia.
Yang WangIcon Cancer Centres, Wahroonga, NSW, Australia.
Cancer Australia · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo present the development of an in-house coded solution for treatment planning of tangential breast radiotherapy that creates single click plans by emulating the iterative optimization process of human dosimetrists.

methodOne hundred clinical breast cancer patients were retrospectively planned with an automated planning (AP) code incorporating the hybrid intensity-modulated radiotherapy (IMRT) approach. The code automates all planning processes including plan generation, beam generation, gantry and collimator angle determination, open segments and dynamic IMRT fluence and calculations. Thirty-nine dose volume histogram (DVH) metrics taken from three international recommendations were compared between the automated and clinical plans (CP), along with median interquartile analysis of the DVH distributions. Total planning time and delivery QA were also compared between the plan sets.

resultsOf the 39 planning metrics analyzed 23 showed no significant difference between clinical and automated planning techniques. Of the 16 metrics with statistically significant variations, 2 were improved in the clinical plans in comparison to 14 improved in the AP plans. Automated plans produced a greater number of ideal plans against international guidelines as per EviQ (AP:77%, CP:68%), RTOG 1005 (AP:80%, CP:71%), and London Cancer references (AP:80%, CP:75%). Delivery QA results for both techniques were equivalent. Automated planning techniques resulted in an average reduction in planning time from 23 to 5 minutes.

conclusionWe have introduced an automated planning code with iterative optimization that produces equivalent quality plans to manual clinical planning. The resultant change in workflow results in a reduction in treatment planning times.

Indexed as

Breast NeoplasmsRadiotherapy, Intensity-ModulatedBreastFemaleHumansRadiotherapy DosageRadiotherapy Planning, Computer-AssistedRetrospective Studiesautomated planningautomationbreast radiotherapyhybrid IMRTradiotherapy planning

Identifiers

PMID33016622
PMCPMC7700918
OpenAlexW3090097849

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.