Evidence map›Paper›PMID 33016307›Full record

ReviewDiseases of the esophagus : official journal of the International Society for Diseases of the Esophagus2021

How to approach adult patients with asymptomatic esophageal eosinophilia.

Philipp Schreiner, Luc Biedermann, Thomas Greuter, Benjamin L Wright, Alex Straumann

Open access · bronzeAbstract readReview
In one paragraph

Review in Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 17 citations in OpenAlex.

  1. Asymptomatic esophageal eosinophilia in oral immunotherapy: context and clinical application.The journal of allergy and clinical immunology. In practice · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Eosinophilic Esophagitis-What Do We Know So Far?Journal of clinical medicine · 2023
    Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Philipp SchreinerDepartment of Gastroenterology & Hepatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Luc BiedermannDepartment of Gastroenterology & Hepatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Thomas GreuterDepartment of Gastroenterology & Hepatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Benjamin L WrightDivision of Allergy, Asthma, and Clinical Immunology, Department of Medicine, Mayo Clinic Arizona, Scottsdale, AZ, USA.
Alex StraumannDepartment of Gastroenterology & Hepatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
University of Zurich · CHWinnMed · US

Funding

TRAINING (CAREER DEVELOPMENT) COMPONENTU54AI117804 · NIAID · CINCINNATI CHILDRENS HOSP MED CTR · PI GLENN T FURUTA, Marc E. Rothenberg · 2014 to 2026
$18.5M
NIAID NIH HHS U54 AI117804
6 · The paper itself

Abstract

As the awareness among gastroenterologists regarding endoscopic features suggesting eosinophilic esophagitis is increasing, individuals without symptoms of esophageal dysfunction are increasingly being found to have esophageal eosinophilia on biopsies performed during upper gastrointestinal endoscopies. However, the course of disease and the management of these asymptomatic individuals with esophageal eosinophilia remain elusive. In this review, we propose a definition of asymptomatic individuals with esophageal eosinophilia and discuss the prevalence, risk factors, and course of disease of this specific patient group. Furthermore, we have established a diagnostic and therapeutic pathway based on the most recent available data.

Indexed as

Eosinophilic EsophagitisAdultBiopsyEndoscopyHumansPrevalenceeosinophilic esophagitiseosinophilic gastrointestinal disorderseosinophils

Identifiers

PMID33016307
PMCPMC7947174
OpenAlexW3090325599

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.