ArticleDiseases of the esophagus : official journal of the International Society for Diseases of the Esophagus2021
Quantitative fluorescence-guided perfusion assessment of the gastric conduit to predict anastomotic complications after esophagectomy.
Article in Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed, 47 citations in OpenAlex.
- Quantitative assessment of gastric tube perfusion during Ivor Lewis esophagectomy using indocyanine-green: results from the prospective interventional trial SPY Q-ICG PAS study.Surgical endoscopy · 2026Trial
- Conduit size and the risk of delayed gastric conduit emptying after esophagectomy.Surgery today · 2026Article
- The Role of Quantitative Indocyanine Green Angiography with Relative Perfusion Ratio in the Assessment of Gastric Conduit Perfusion in Oesophagectomy: A Retrospective Study.Journal of clinical medicine · 2025Article
- Advances in Minimally Invasive Esophagectomy-An Overview of Recent Developments and a Novel Classification of Innovations in Treatment of Thoracic Esophageal Cancer.Medicina (Kaunas, Lithuania) · 2025Review
- Multi-exposure speckle imaging through an optical fiber bundle.Journal of biomedical optics · 2025Article
- Risk Factors for Benign Anastomotic Stenosis After Esophagectomy for Cancer.Annals of surgical oncology · 2025Article
- The role of ICG NIRL fluorescence imaging in the surgical treatment of digestive system tumors (Review).Molecular medicine reports · 2025Review
- Evaluating Postoperative Morbidity and Outcomes of Robotic-Assisted Esophagectomy in Esophageal Cancer Treatment-A Comprehensive Review on Behalf of TROGSS (The Robotic Global Surgical Society) and EFISDS (European Federation International Society for Digestive Surgery) Joint Working Group.Current oncology (Toronto, Ont.) · 2025Review
- Indocyanine green and near-infrared fluorescence-guided surgery for gastric cancer: a narrative review.Journal of minimally invasive surgery · 2024Review
- Imaging technology to assess tissue oxygen saturation of the gastric conduit in thoracic esophagectomy.JTCVS techniques · 2024Article
- Current status and future trends of real-time imaging in gastric cancer surgery: A literature review.Heliyon · 2024Review
- Quantification of fluorescence angiography for visceral perfusion assessment: measuring agreement between two software algorithms.Surgical endoscopy · 2024Article
- Intraoperative assessment of anastomotic blood supply using indocyanine green fluorescence imaging following esophagojejunostomy or esophagogastrostomy for gastric cancer.Frontiers in oncology · 2024Article
- The use of indocyanine green (ICYG) angiography intraoperatively to evaluate gastric conduit perfusion during esophagectomy: does it impact surgical decision-making?Surgical endoscopy · 2023Article
- Perfusion assessment by fluorescence time curves in esophagectomy with gastric conduit reconstruction: a prospective clinical study.Surgical endoscopy · 2023Article
- Trends in surgical techniques for the treatment of esophageal and gastroesophageal junction cancer: the 2022 update.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2023Article
- Fluorescent Imaging in Visceral Surgery: Current Opportunities and Future Perspectives.Visceral medicine · 2023Review
- The role of fluorescence angiography in colonic interposition after esophagectomy.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2023Article
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFluorescence angiography (FA) assesses anastomotic perfusion during esophagectomy with gastric conduit reconstruction, but its interpretation is subjective. This study evaluated time to fluorescent enhancement in the gastric conduit, with the aim to determine a threshold to predict postoperative anastomotic complications.
methodsIn a prospective cohort study, all consecutive patients undergoing esophagectomy with gastric conduit reconstruction from July 2018 to October 2019 were included. FA was performed before anastomotic reconstruction following injection of indocyanine green (ICG). During FA, the following time points were recorded: ICG injection, first fluorescent enhancement in the lung, at the base of the gastric conduit, at the planned anastomotic site, and at ICG watershed or in the tip of the gastric conduit. Anastomotic complications including anastomotic leakage and clinically relevant strictures were documented.
resultsEighty-four patients were included, the majority (67 out of 84, 80%) of which underwent an Ivor Lewis procedure. After a median follow-up of 297 days, anastomotic leakage was observed in 12 out of 84 (14.3%) and anastomotic stricture in 12 out of 82 (14.6%). Time between ICG injection and enhancement in the tip was predictive for anastomotic leakage (P = 0.174, area under the curve = 0.731), and a cut-off value of 98 seconds was derived (specificity: 98%). All times to enhancement at the planned anastomotic site and ICG watershed were significantly predictive for the occurrence of a stricture, however area under the curves were <0.7.
conclusionsThe identified fluorescent threshold can be used for intraoperative decision making or to identify potentially high-risk patients for anastomotic leakage after esophagectomy with gastric conduit reconstruction.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.