Evidence map›Paper›PMID 33016245›Full record

ArticleVeterinary pathology2020

Altered Basal Autophagy Affects Extracellular Vesicle Release in Cells of Lagotto Romagnolo Dogs With a Variant

Pernilla Syrjä, Mari Palviainen, Tarja Jokinen, Kaisa Kyöstilä, Hannes Lohi, Petra Roosje, Linda Anderegg, Tosso Leeb, Antti Sukura, Eeva-Liisa Eskelinen

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Veterinary pathology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. An update on autophagy disorders.Journal of inherited metabolic disease · 2025
    Review
  2. Review
  3. Polioencephalopathy in Eurasier dogs.Journal of veterinary internal medicine
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Pernilla Syrjä3835University of Helsinki, Helsinki, Finland.ORCID 0000-0001-9740-2636
Mari Palviainen3835University of Helsinki, Helsinki, Finland.
Tarja Jokinen3835University of Helsinki, Helsinki, Finland.
Kaisa Kyöstilä3835University of Helsinki, Helsinki, Finland.
Hannes Lohi3835University of Helsinki, Helsinki, Finland.
Petra Roosje27210University of Bern, Bern, Switzerland.
Linda Anderegg27210University of Bern, Bern, Switzerland.
Tosso Leeb27210University of Bern, Bern, Switzerland.
Antti Sukura3835University of Helsinki, Helsinki, Finland.
Eeva-Liisa Eskelinen3835University of Helsinki, Helsinki, Finland.
University of Helsinki · FIUniversity of Bern · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lagotto Romagnolo breed dogs develop a progressive neurological disease with intracellular vacuolar storage when homozygous for a variant in the autophagy-related gene 4D (

Indexed as

Dog DiseasesExtracellular VesiclesLysosomal Storage DiseasesAnimalsAutophagyDogsFemaleLysosomesMaleVacuolesATG4Dbasal autophagycaninedisease modelextracellular vesiclesimmunoelectron microscopymass spectrometryNTA

Identifiers

PMID33016245
PMCPMC7747043
OpenAlexW3091226994

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.