ReviewJournal of experimental zoology. Part B, Molecular and developmental evolution2021
Molecular mechanisms and evolution of fertilization proteins.
Review in Journal of experimental zoology. Part B, Molecular and developmental evolution, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed, 35 citations in OpenAlex.
- Female genetic variation controlling timing of mating plug ejection inbioRxiv : the preprint server for biology · 2026Article
- Research progress on serine proteases in the field of male reproduction: a narrative review.Translational andrology and urology · 2026Review
- Molecular evolution of octopamine receptors in Drosophila.G3 (Bethesda, Md.) · 2026Article
- TheBiomolecules · 2025Review
- Genetic variation in zona pellucida-3 (ZP3) gene and its association with litter size variation in Kari sheep.Animal biotechnology · 2025Article
- Correlated Gene Copy Number Changes in a Seminal Fluid Protein Network inbioRxiv : the preprint server for biology · 2025Article
- Molecular evolution of octopamine receptors inbioRxiv : the preprint server for biology · 2025Article
- Sexual selection and pseudogenization in primate fertilization.Evolution; international journal of organic evolution · 2025Article
- Comparative functional analyses of the prostate-specific KLK3 enzyme in primates reveal the impact of sexual selection.Evolution; international journal of organic evolution · 2025Article
- Recurrent Independent Pseudogenization Events of the Sperm Fertilization Gene ZP3r in Apes and Monkeys.Journal of molecular evolution · 2024Article
- Refinement of the Antarctic fur seal (Arctocephalus gazella) reference genome increases continuity and completeness.G3 (Bethesda, Md.) · 2024Article
- Synthesis and Scope of the Role of Postmating Prezygotic Isolation in Speciation.Cold Spring Harbor perspectives in biology · 2024Review
- Review
- Article
- FREEDA: An automated computational pipeline guides experimental testing of protein innovation.The Journal of cell biology · 2023Article
- A New GeneInternational journal of molecular sciences · 2023Article
- FREEDA: an automated computational pipeline guides experimental testing of protein innovation by detecting positive selection.bioRxiv : the preprint server for biology · 2023Article
- Positive selection on ADAM10 builds species recognition in the synchronous spawning coralFrontiers in cell and developmental biology · 2023Article
- A comprehensive investigation of human endogenous retroviral syncytin proteins and their receptors in men with normozoospermia and impaired semen quality.Journal of assisted reproduction and genetics · 2023Article
- Domain Expansion and Functional Diversification in Vertebrate Reproductive Proteins.Molecular biology and evolution · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Sexual reproduction involves a cascade of molecular interactions between the sperm and the egg culminating in cell-cell fusion. Vital steps mediating fertilization include chemoattraction of the sperm to the egg, induction of the sperm acrosome reaction, dissolution of the egg coat, and sperm-egg plasma membrane binding and fusion. Despite decades of research, only a handful of interacting gamete recognition proteins (GRPs) have been identified across taxa mediating each of these steps, most notably in abalone, sea urchins, and mammals. This review outlines and compares notable GRP pairs mediating sperm-egg recognition in these three significant model systems and discusses the molecular basis of species-specific fertilization driven by GRP function. In addition, we explore the evolutionary theory behind the rapid diversification of GRPs between species. In particular, we focus on how the coevolution between interacting sperm and egg proteins may contribute to the formation of boundaries to hybridization. Finally, we discuss how pairing structural information with evolutionary insights can improve our understanding of mechanisms of fertilization and their origins.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.