Observational studyActa anaesthesiologica Scandinavica2021
Indexing haemodynamic variables in young children.
Observational study in Acta anaesthesiologica Scandinavica, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Early exposure, enduring consequences: How do I manage Rh immunoglobulin prophylaxis after Rh-mismatched transfusions in children?Transfusion · 2026Article
- Determination of cardiac output, shunt-fraction, and active circulatory volume in children with hypoplastic left heart syndrome after the Norwood procedure with RV to PA-shunt.Scientific reports · 2026Article
- Indexing haemodynamic variables in young children.Acta anaesthesiologica Scandinavica · 2021Observational
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Authors and funding
2 authors.
Funding
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Abstract
backgroundHaemodynamic studies in children are rare and most studies have included few subjects in the youngest age group. Haemodynamic variables need to be indexed to establish a reference of normality that is valid in all populations. The traditional way to index haemodynamic variables with body surface area (BSA) is complicated in young children due to its non-linear relationship with body weight (BW). We examined several haemodynamic variables in children by indexing them with BSA and BW.
methodsA single-centre, observational cohort study comparing non-indexed and indexed haemodynamic variables in children undergoing heart surgery (divided into three weight groups: 1-5 kg, >5-10 kg and >10-15 kg).
resultsA total of 68 children were included in this study, mean age 11.1 months ± 11.1 month (range 0 to 43 months). All haemodynamic variables, cardiac output (CO), stroke volume (SV), total end-diastolic volume (TEDV), central blood volume (CBV) and active circulation volume (ACV), increased with weight without indexing (P < .05). Indexing variables with BW produced a more linear relationship for all haemodynamic variables between weight groups than BSA. The mean BSA-indexed haemodynamic values were CI
conclusionsIndexing haemodynamic variables with BW produces a more appropriate body size-independent scale in young children than BSA. SUMMARY STATEMENT: In this study, we studied indexing of haemodynamic variables and estimation of blood volumes in young children undergoing corrective heart surgery using an indicator dilution technology.
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